Biocatalysts

BBiocatalysts are essential tools in chemical synthesis, particularly in the synthesis of pharmaceutical and fine chemical targets.As highly selective catalysts, they offer a direct and simple way to synthesise complex achiral and chiral compounds. The application of biocatalysts in the pharmaceutical and ...

Purified Talc BP/USP/EP/JP

H2BioCat is an enzyme on carbon biocatalyst system for highly selective chemical synthesis via hydrogen-driven cofactor supply to any NADH/Flavin dependent redox enzyme
• 100% atom efficient cofactor recycling: mitigates waste from typical carbon based reductants for biocatalysis (glucose / alcohol) ...

Readily available and fully optimised immobilized enzymes, ready to use for R&D and possibility for tailoring and scale up. The first iteration of the catalogue focuses in (1) cofactor regeneration, (2) detoxification and (3) protein and peptide degradation. 

You have a challenging (non-natural) reaction and wonder if there is an enzyme capable of doing it? Or you already have an enzyme but its performance or stability in underwhelming and there might be a better version out there in nature?

We employ the latest technology in biophysics and m...

We offer tailor made screenings of internal and external enzyme panels to identify applicable off-the-shelf biocatalysts for your target reaction. We integrate analytical services such as method development and validation throughout the process to get a reliable statement about the feasibility of your ...

Enzymes for biocatalysis Diverse biotransformations
Please reach out for details

Bio2Amine™ is an enzyme on carbon hydrogenation catalyst with similar handling to common precious-metal on carbon catalysts. Using HydRegen technology to provide industrial reactions under mild conditions we are:
• Lowering energy requirements and, improving specificity • Bio2Amine™ is recommende...

Mesalazine (mesalamine, 5-aminosalicylic acid)
Pharmaceutical indicated for ulcerative colitis, Crohn’s disease, inflammatory bowel disease.
For the reduction of 5-nitrosalicylic acid (5-NSA), Bio2Amine™ facilitates highly selective hydrogenation to 5-aminosalicylic wit...

Your biocatalytic process does not meet economic targets or is generally inefficient? The amount of enzyme formulated in your product is too high leading to increased cost of goods?

Boost your enzyme’s performance and stability with the latest advancements in biophysics and AI.
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Do you want to squeeze the maximum out of your enzyme?
Ever wondered what the true best mutations within your enzyme are?

We specialize in the generation of Recombinatorial Libraries and Holistic Libraries of any size and shape for your enzyme in E. coli or Pichia.

M...

KGOs (short for Fe/ketoglutarate-dependent oxygenases) are known to stereo- and regioselectively catalyze

• Hydroxylation • Epoxidation
reactions and are thus an excellent addition or replacement to traditional chemical processes.

KGOs are intracellular enzymes and t...

UPOs (short for Unspecific Peroxygenases) are known to stereo- and regioselectively catalyze

• Hydroxylation • Epoxidations • Dealkylation • Heteroatom oxygenation (e.g. sulfoxidation)
reactions and are thus an excellent addition or replacement to traditional chemical processe...

We offer technical demonstration of biotechnological processes up to the kg scale and are your experienced partner in scaling up processes for enzyme production and/or application of enzyme technology. Our independent approach always allows us to use the most suitable strategy to serve your specific de...

Inspired by solutions found in biological systems, we are proficient in developing robust chemo-enzymatic processes to produce your target compound. A strong platform on biocatalytic transformations and the ability to develop novel bio-inspired synthesis strategies for your product are our unique selli...

Is the enzyme you are interested in not commercially available and a production needs to be developed? Enzymicals has extensive expertise with scale-up from lab to pilot-scale and technology transfers to industrial manufacturing sites. We can supply your protein by in-house production up to the kg-scale...

We develop enzymes for a variety of industries using a proven platform to access unique enzymes from biodiversity. Sequence- and function-driven approaches are ready to support the creation of novel panels of biocatalysts with focus on a single asset with FTO or a strong patent position.

Enzymes for diverse applicationsPlease reach out for more information