Scale-up and demonstration of biotechnological processes
Product Description
Enzymicals AG
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DE -
2015On CPHI since
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1 - 24Employees
Company types
Primary activities
Categories
Specifications
Enzymicals AG
-
DE
-
2015On CPHI since
-
1 - 24Employees
Company types
Primary activities
More Products from Enzymicals AG (12)
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Product Enzyme screening & proof-of-concept studies
We offer tailor made screenings of internal and external enzyme panels to identify applicable off-the-shelf biocatalysts for your target reaction. We integrate analytical services such as method development and validation throughout the process to get a reliable statement about the feasibility of your ... -
Product Development of chemo-enzymatic processes
Inspired by solutions found in biological systems, we are proficient in developing robust chemo-enzymatic processes to produce your target compound. A strong platform on biocatalytic transformations and the ability to develop novel bio-inspired synthesis strategies for your product are our unique selli... -
Product Enzyme development
We develop enzymes for a variety of industries using a proven platform to access unique enzymes from biodiversity. Sequence- and function-driven approaches are ready to support the creation of novel panels of biocatalysts with focus on a single asset with FTO or a strong patent position.
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Product Biocatalyst production
Is the enzyme you are interested in not commercially available and a production needs to be developed? Enzymicals has extensive expertise with scale-up from lab to pilot-scale and technology transfers to industrial manufacturing sites. We can supply your protein by in-house production up to the kg-scale... -
Product Enzyme screening kits
Diverse off the shelf screening kits -
Product Amine transaminases
Enzymicals AG provides wide range of enzymes which includes amine transaminases. It catalyse the transfer of an amino group from a primary amine to a prochiral ketone (or aldehyde). Amine transaminases are highly enantioselective and therefore can be used for the resolution of racemic amines or the synthes... -
Product Imine reductases
Enzymatic asymmetric imine reduction is a promising alternative for the synthesis of chiral amines. Imine reductases (IREDs) catalyze the reduction of imines to amines by using NAD(P)H as a hydride source. These enzymes are classified as EC 1.5.1.48, alongside other enzymes with imine-forming and imine-red... -
Product Carboxylesterasen
Enzymicals AG provides wide range of enzymes which includes carboxylesterasen. It is a subset of hydrolases, find broad application in organic synthesis. Due to their high regio- and stereoselectivity they are used for the selective cleavage of protecting groups and for the kinetic resolution of esters of ... -
Product Lipases
Lipases (EC 3.1.1.3) catalyze the hydrolysis of water-insoluble esters such as triglycerides like triolein to diolein. In addition, lipases also convert a broad range of natural and unnatural esters, while retaining high enantio- or regioselectivity. They require no cofactors and are stable and act... -
Product Halohydrindehalogenasen
Enzymicals AG provides wide range of enzymes which includes halohydrindehalogenasen. They are bacterial enzymes that are belong to the class of lyases (EC 4.5.1) and which have naturally involved in the mineralization of halogenated xenobiotics. They exhibit high regio- and enantioselectivity towards aliph... -
Product Phosphotransferases
Phosphotransferases (EC 2.7) catalyze the transfer of phosphate groups from phosphate-donating molecules to specific substrates. This process is known as phosphorylation, where the substrate gains a phosphate group and a specific donor molecule provides a phosphate group. Biocatalytic phosphorylati... -
Product Enzyme technologies for small molecule synthesis
We offer one of the larges off-the-shelf collections for your development program. The collection includes more than 3,500 enzymes in over 50 enzyme panels ready for application.
The collection contains among others:
Ketoreductases: 700+ enzymes
Imine re...
Frequently Viewed Together
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Product Technology Transfer | CMO | Regenerative Medicine-Medical devices | from...
Our Expertise in BIOMATERIALS for your Medical ApplicationsWe develop, manufacture and technology transfer for-Viscosupplements (Intra Articular Gels)-Dermal Fillers-Viscoelastics - ophthalmoogy-Adhesion Barrier-Hydrogel for Vesicoureteral Reflux (VUR) applications-Hydrogels for treatment of Intercystitial...
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Product RoSS.pFTU: Controlled Freezing & Thawing Platform
The plate-based freeze-thaw platforms from Single Use Support enable controlled freezing and thawing of drug substances. Transferable recipes enable full scalability and compatibility from the lab to blockbuster production. Thanks to RoSS technology all batch sizes and single-use bags from all establi...
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Product WAB IMPA°CT REACTOR
An inductively heated mechanochemical reactor for continuous mechanochemistry, the WAB IMPA°CT REACTOR is our latest innovation in the field of flow chemistry. An induction heater arranged around the stirring elements heats the reactants directly and efficiently up to +160 °C.
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Product Sterile drug product CDMO services
Thermo Fisher Scientific's flexible aseptic manufacturing and sterile fill finish solutions for your molecule’s unique needs and challenges will enable success in early development, late-phase, and commercial manufacturing.
Thermo Fisher offers extensive sterile product development and commercial ...
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Product Tech Transfer and Scale Up
Tech Transfer and Scale up to support clinical and commercial programs
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Product Gobi Gold Daily Balancer(R)
Incorporating PRT(R) Beads and Fusion Technology(R) in Gobi Gold Daily Balancer(R)enabled us to combine the essential fat-soluble and water-soluble nutrientsin ONE capsule simplifying dosing schedule without exceeding therecommended daily dose. We succeeded to combine materials with different properties an...
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Product Research & Development
Avéma offers formulation, process and analytical development support of new or existing products using the most current and effective active ingredients and delivery systems. Our team of scientists bring decades of pre-formulation development expertise to your products, combined with the knowledge of how t...
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Product Biocatalysis Solutions
BBiocatalysts are essential tools in chemical synthesis, particularly in the synthesis of pharmaceutical and fine chemical targets.As highly selective catalysts, they offer a direct and simple way to synthesise complex achiral and chiral compounds. The application of biocatalysts in the pharmaceutical and ...
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Product Biosimilars Testing Services
Testing services for biosimilars: Our biosimilar analytical comparability programs provide highly relevant data for early stage characterisation and later stage comparison. These programs evaluate and compare all pertinent features of the biosimilar product and are based on the ICH Q6B. Programs encompa...
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Product ReliZymeTM Enzyme Carrier product line
ReliZyme™ are Resindion products designed for biocatalytic applications. These products are developed for the optimal immobilization of every kind of enzyme thanks to the availability of different chemical linker and/or modulation of the hydrophilic/hydrophobic balance and porosity ...
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Product Biologic drug substance CDMO services
From pre-clinical development to commercial supply, Patheon by Thermo Fisher Scientific is an industry leader in the development and manufacture of mammalian cell culture drug substances. Patheon offers biotech and pharmaceutical companies the ability to pursue opportunities around the globe with a fully i...
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Product Enzyme Libraries
Do you want to squeeze the maximum out of your enzyme?
Ever wondered what the true best mutations within your enzyme are?
We specialize in the generation of Recombinatorial Libraries and Holistic Libraries of any size and shape for your enzyme in E. coli or Pichia.
M...
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Product Tablets & Capsules
Unither Pharmaceuticals is able to provide a range of flexible services in the production of tablets and capsules. We can work with you from the earliest stages of R&D to create a new dry form, or we can be your partner in reformulating or packaging an existing product.
Advantages :
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Product Food safety evaluation
Potential benefits and safety of dietary supplements need to be assessed by scientifically validated means, in the context of Regulation (EC) 2015/2283 on novel foods. Toxicological data, including genotoxicity, information on absorption, distribution, metabolism and excretion (ADME) need to be collecte...
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Product Biocatalytic R&D servcies
Enzyme screening and R&D services
Enzyme custom development and enzyme manufacturing
Routescouting, enzyme discovery and improvement Bulk enzyme supplier
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Product Biocatalyst production
Is the enzyme you are interested in not commercially available and a production needs to be developed? Enzymicals has extensive expertise with scale-up from lab to pilot-scale and technology transfers to industrial manufacturing sites. We can supply your protein by in-house production up to the kg-scale...
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Product Bio2Amine for Mesalazine (mesalamine)
Mesalazine (mesalamine, 5-aminosalicylic acid)
Pharmaceutical indicated for ulcerative colitis, Crohn’s disease, inflammatory bowel disease.
For the reduction of 5-nitrosalicylic acid (5-NSA), Bio2Amine™ facilitates highly selective hydrogenation to 5-aminosalicylic wit...
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Product Pharmaceutical development (CDMO) & Exclusive portfolio
From research, pre-formulation, and formulation development, up to commercial manufacturing (including HPAPI).
Bluepharma offers an integrated drug development service (CDMO) from research, pre-formulation, and formulation development, up to commercial manufacturing ...
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Product Enzyme Discovery
You have a challenging (non-natural) reaction and wonder if there is an enzyme capable of doing it? Or you already have an enzyme but its performance or stability in underwhelming and there might be a better version out there in nature?
We employ the latest technology in biophysics and m...
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Product Scale-up and Quality by Design (QbD) processes
Skyepharma is experienced with the scale-up of complex oral solid dosage forms from laboratory to pilot-scale and full commercial scale manufacturing. We have powerfull compaction simulation tools ( STYL'One evolution) allowing to derisk and fasten scale-up steps.
Our capabilities :...
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Product Incubator shaker
The ISF1-Z incubator shaker is suitable for applications in laboratories, research centers and production facilities. The ISF1-Z complies with GMP (good manufacturing practice) requirements and regulations. It offers a large shaking capacity with a small footprint and many features allowing straightforward...
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Product Suppositories & Pessaries
Suppositories and pessaries are an ideal method of administration for a drug when the oral route is not possible due to nausea or vomiting. This is one of the best ways to avoid the first-path effect, which lowers the efficacy of a drug product. Unither has many years of experience in the manufacture of su...
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Product Chemistry Compatible Process Vacuum Pump
In addition to the VACUUBRAND's proven chemistry diaphragm vacuum pumps we have added a new VAC 24seven series, which is now available for pilot and industrial scale applications. The proven reliability of our individual pumps has been combined to produce a powerful modular process vacuum system. F...
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Product Safety and Toxicity in vitro
We are a GLP lab providing safety assessment and toxicological tests in vitro for cosmetics, pharmaceutical, medical devices and chemical products. The tests included covers a wide range of targets including reprodutive toxicity tests for intimate lubricants. We are a EU-NETVAL member working with the Euro...
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Product Biocatalyst: KGO Enzyme Panel 20
KGOs (short for Fe/ketoglutarate-dependent oxygenases) are known to stereo- and regioselectively catalyze
• Hydroxylation • Epoxidation
reactions and are thus an excellent addition or replacement to traditional chemical processes.
KGOs are intracellular enzymes and t...
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Product SEITzyme catalogue of immobilized enzymes
Readily available and fully optimised immobilized enzymes, ready to use for R&D and possibility for tailoring and scale up. The first iteration of the catalogue focuses in (1) cofactor regeneration, (2) detoxification and (3) protein and peptide degradation.
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Product Enzyme Engineering with AI
Your biocatalytic process does not meet economic targets or is generally inefficient? The amount of enzyme formulated in your product is too high leading to increased cost of goods?
Boost your enzyme’s performance and stability with the latest advancements in biophysics and AI.
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Product Ambr® 250 High Throughput Perfusion
Ambr® 250 High Throughput Perfusion is a parallel bioreactor system for rapid development of scalable perfusion processes using 100 – 250 mL single-use bioreactors and a fully automated liquid handling platform.The system supports the typical range of hollow fibre cell retention applications, wit...
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Product Liquid Stick-Pack
Unither is a referent for liquid stick-pack technology thanks to its multidisciplinary and international team.
Liquid stick-packs deliver just the right dose for precise dosage. Packaging protects contents from moisture, oxygen and light.
Thanks to its small size and compactn...
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Product Bio2Amine: nitro-to-amine reduction
Bio2Amine™ is an enzyme on carbon hydrogenation catalyst with similar handling to common precious-metal on carbon catalysts. Using HydRegen technology to provide industrial reactions under mild conditions we are:
• Lowering energy requirements and, improving specificity • Bio2Amine™ is recommende...
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Product Biocatalytic enzymes for small molecule manufacturing
Ketoreductases (>250 enzymes)
Transaminases (>100 enzymes)
EsterasesandLipases(60enzymes)
Nitrilases(>20enzymes),Amidases(10enzymes)
Oxidases
ENE-Reductases(20enzymes)
Lactate dehydrogenase, Format dehydrogenase, Glucose
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Product GCP/GLP Bioanalysis Services
In our state-of-the-art facilities, we provide GLP/GCP method development, validation, method transfer, sample analysis and pharmacokinetic and toxicokinetic support, along with automated data collection and reporting systems. Over the past 20 years, we have supported the development of pharmaceuticals, bi...
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Product Amine transaminases
Enzymicals AG provides wide range of enzymes which includes amine transaminases. It catalyse the transfer of an amino group from a primary amine to a prochiral ketone (or aldehyde). Amine transaminases are highly enantioselective and therefore can be used for the resolution of racemic amines or the synthes...
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Product Spray
Unither Liquid Manufacturing (ULM) is a production site of Unither Group. ULM is dedicated to the development and manufacture of health products in semi solid and liquid forms, such as nasal sprays. Nasal spray humidifies, cleans, decongests and purifies the nasal cavities to improve breathing. It is ...
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Product Biocatalyst: UPO Enzyme Panel 77
UPOs (short for Unspecific Peroxygenases) are known to stereo- and regioselectively catalyze
• Hydroxylation • Epoxidations • Dealkylation • Heteroatom oxygenation (e.g. sulfoxidation)
reactions and are thus an excellent addition or replacement to traditional chemical processe...
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Product H2BioCat: asymmetric reductions
H2BioCat is an enzyme on carbon biocatalyst system for highly selective chemical synthesis via hydrogen-driven cofactor supply to any NADH/Flavin dependent redox enzyme
• 100% atom efficient cofactor recycling: mitigates waste from typical carbon based reductants for biocatalysis (glucose / alcohol) ...
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Product Customized immobilized products
A customer oriented policy and a quick customized product development are some of RDN strengths, made possible thanks to the support of a pilot plant for the scale-up and a very skilled R&D technical team . Thanks to the importance that RESINDION places in focusing on R&D activities, we ...
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Product Enzymes for the degradation of CN, OCN and SCN
Cyanase Enzymes for the degradation of CN, OCN and SCN
Potential Applications:
Detoxification of excess NaCN after cyanation reaction
Detoxification of NaCN in aqueous waste waters
Detoxification of metal CN complex solutions (wastes of electroplating proces...
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