Enzyme development

We offer tailor made screenings of internal and external enzyme panels to identify applicable off-the-shelf biocatalysts for your target reaction. We integrate analytical services such as method development and validation throughout the process to get a reliable statement about the feasibility of your ...

Inspired by solutions found in biological systems, we are proficient in developing robust chemo-enzymatic processes to produce your target compound. A strong platform on biocatalytic transformations and the ability to develop novel bio-inspired synthesis strategies for your product are our unique selli...

We offer technical demonstration of biotechnological processes up to the kg scale and are your experienced partner in scaling up processes for enzyme production and/or application of enzyme technology. Our independent approach always allows us to use the most suitable strategy to serve your specific de...

Is the enzyme you are interested in not commercially available and a production needs to be developed? Enzymicals has extensive expertise with scale-up from lab to pilot-scale and technology transfers to industrial manufacturing sites. We can supply your protein by in-house production up to the kg-scale...

Diverse off the shelf screening kits

Enzymicals AG provides wide range of enzymes which includes amine transaminases. It catalyse the transfer of an amino group from a primary amine to a prochiral ketone (or aldehyde). Amine transaminases are highly enantioselective and therefore can be used for the resolution of racemic amines or the synthes...

Enzymatic asymmetric imine reduction is a promising alternative for the synthesis of chiral amines. Imine reductases (IREDs) catalyze the reduction of imines to amines by using NAD(P)H as a hydride source. These enzymes are classified as EC 1.5.1.48, alongside other enzymes with imine-forming and imine-red...

Enzymicals AG provides wide range of enzymes which includes carboxylesterasen. It is a subset of hydrolases, find broad application in organic synthesis. Due to their high regio- and stereoselectivity they are used for the selective cleavage of protecting groups and for the kinetic resolution of esters of ...

Lipases (EC 3.1.1.3) catalyze the hydrolysis of water-insoluble esters such as triglycerides like triolein to diolein. In addition, lipases also convert a broad range of natural and unnatural esters, while retaining high enantio- or regioselectivity. They require no cofactors and are stable and act...

Enzymicals AG provides wide range of enzymes which includes halohydrindehalogenasen. They are bacterial enzymes that are belong to the class of lyases (EC 4.5.1) and which have naturally involved in the mineralization of halogenated xenobiotics. They exhibit high regio- and enantioselectivity towards aliph...

Phosphotransferases (EC 2.7) catalyze the transfer of phosphate groups from phosphate-donating molecules to specific substrates. This process is known as phosphorylation, where the substrate gains a phosphate group and a specific donor molecule provides a phosphate group. Biocatalytic phosphorylati...

We offer one of the larges off-the-shelf collections for your development program. The collection includes more than 3,500 enzymes in over 50 enzyme panels ready for application.

The collection contains among others:

Ketoreductases: 700+ enzymes
Imine re...