Wet Polishing

Particle Engineering Technologies
We specialize in particle engineering technologies to address oral bioavailability, lung delivery, modified release and taste masking. In each technology we can support you from proof of concept to commercial manufacturing.
Wet Polishing
Hovione developed wet polishing as a solution for generating 100% stable crystalline material which is recovered utilizing a spray drying process.

Wet polishing is a process that combines two integrated technologies: one to attain a small particle size (either a bottom-up technique such as controlled crystallization or nanocrystallization or top down technique such as high shear mixing or high pressure homogenization); and two to isolate the particles (for example spray drying or filtration followed by a drying process). This combination can be used to fine tune particle size and morphology in order to meet specific drug delivery requirements.

Applications
Powders for inhalation
Powders with very tight particle size distributions

Micronized powders for oral delivery
Micro- and nanoparticles used to overcome solubility limitations of BCS class 2 and 4 drugs