Sirio’s Ayanda launches probiotic softgel

Patent-pending technology is the first ever to enable a softgel capsule to contain both probiotic bacteria and Omega 3 oil.
Ayanda – the European headquarters of the Sirio Group, a global nutraceutical contract development, innovation and manufacturing organization (CDiMO) – has secured a European patent for softgel capsules able to contain an active probiotic bacteria, as well as at least one oil (e.g., Omega 3). This is a breakthrough in the group’s ability to develop and deliver a new probiotic dosage form – adding to the company's existing probiotic capabilities in hard capsules, tablets and powdersticks. This nutraceutical innovation will be unveiled to the wider market for the first time at Vitafoods Europe on May 8th at 1 pm.
Until now, softgel capsules were required to be manufactured at high temperatures and humidity, which leads to the destruction of probiotics, meaning softgel probiotic formulations were unviable. Ayanda however, has spent 10-years perfecting its new approach using a gentle method, whereby the survival rate of probiotics is vastly increased. The innovation enables the manufacture of softgel capsules comprising uncoated probiotic bacteria alongside at least one oil – e.g. fish oil with DHA and EPA, and vitamins in one single softgel.
Creation of the patented process was achieved by optimally adjusting to the specific characteristics of probiotics, which uniquely minimises the loss of viable cells during production. Ayanda designed process parameters that dramatically improve survival rates and defined packaging and storage conditions accordingly.
Ahead of the new innovations unveiling at Vitafoods Europe, Dr Dominique Baum, Managing Director at Ayanda, commented: “The industry has spent a long time trying to develop a product like this, and using this new production method we are able to balance the survival of probiotics and the formation of an intact softgel capsule – so it is a big achievement. It will enable Ayanda to offer unique softgel probiotics coupled with an additional oil – crucially reducing the number of dosages consumers need to get their supplement needs. With this new technology, we expect to see a large interest from nutraceutical brand owners, as it opens up many possibilities for truly novel products.”
The European Patent Office has published the listing in the European Patent Bulletin for “an improved process for producing a softgel capsule comprising viable probiotic bacteria and a softgel comprising viable probiotic bacteria with a long shelf life”.
Ayanda’s core business is the development and manufacture of complex softgels containing up to 10 or more ingredients. This new technology forms part of a wider innovation strategy and corporate culture at Ayanda and Sirio – following the announcement of the company’s enhanced global R&D group in early April – with both European and China teams currently undertaking proactive research on a number of projects. These include the creation of new nutraceutical dosage forms and formulations to help customers advance products to market faster.
“We started this particular project with the simple goal of trying to combine the advantages of Omega 3 fatty acids and probiotics in one single softgel capsule. For consumers there is a clear gap in the market, as at present they need two different dosages. But for brand owners, this opens-up many customer segments from the ‘unborn child and mother’ to all adults thoughtful of preserving vitality, vision and vascular health. Making both components available in one capsule represents a valuable addition to healthcare,” added Baum.

Related News
-
News Pfizer may shift production back to US under Trump pharma tariffs
At the 45th TD Cowen annual healthcare conference in Boston, USA, Pfizer CEO Albert Bourla outlined the potential for Pfizer to shift its overseas drug manufacturing back to the US as pharmaceutical industry players weigh their options against Presiden... -
News Women in Pharma: Connecting accessible pharma packaging to patients – a Pharmapack Special
Throughout our Women in Pharma series, we aim to highlight how CPHI events encourage discussions around diversity, equity, and inclusion initiatives in the pharmaceutical industry. -
News CPHI Podcast Series: Packaging expert perspectives at Pharmapack 2025
This month's podcast episode sounds a little different, covering the latest event in Paris – Pharmapack 2025. Digital Editor Lucy Chard speaks to several experts direct from the floor of the show, bringing you right in on the action.&nbs... -
News Closing 2024 with Editors' picks of top articles from the past year
Coming to the end of 2024 and it’s certainly been a busy year, for CPHI and for the rest of the pharmaceutical and healthcare industry. Topics of conversation throughout the last 12 months have been varied, touching on the technical, to the polit... -
News SCHOTT Pharma’s sustainable journey with CPHI
Sustainability is of paramount importance in the pharmaceutical industry. See how a recent partnership between CPHI and SCHOTT Pharma has helped to highlight and accelerate their sustainability journey to reach global goals. -
News CPHI Podcast Series: Investing in a vision for the future of life sciences
In this episode Lucy Chard is joined by Rajiv Khatau to discuss the importance of looking into new therapeutic areas and some of the more niche areas of pharmaceuticals, and investing in the future of the industry. -
News Lessons from CPHI Milan 2024: Sunny Intervals for Pharma Manufacturing?
As the 2024 CPHI conference wrapped up in Milan, we caught up with L.E.K. Consulting – a global strategy consulting firm with deep expertise in pharma manufacturing – to discuss evolving market perspectives and business outlook. -
News Women in Pharma: Reflections from Behind the Scenes
In this instalment of our monthly series, the team that brings you the Women in Pharma series each month sits down for a heart-to-heart on what the series means to them, and how they hope to continue their work in the future.
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance