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Overview Products and Services Continuous Manufacturing

Overview Products and Services Continuous Manufacturing
Product Description

PROCESS RESEARCH 

Development of efficient synthesis routes using the advantages of continuous processing. 

PROCESS DESIGN

Decades of experience in process intensification, flow chemistry and continuous processing gives us the ability to investigate the best approach and strategy to put your process into an efficient system.

CHEMICAL AND TECHNICAL FEASIBILITY

Inside our flow lab scale plants we have multiple technologies available to develop continuous experimental procedures with the principal objective of showing a reliable mode of operation.

OPTIMIZATION & PILOT PHASE

Depending on the inherent characteristics each verified continuous process is optimized. The optimal processing window is determined on scalable equipment to finally deliver a robust continuous system.

PLANT REALIZATION

Our engineering team develops, designs and realizes continuous modular laboratory, pilot and manufacturing plants. According to requirements, the plants feature CE, ATEX or GMP compliance.

Microinnova Engineering GmbH

  • AT
  • 2015
    On CPHI since
  • 5
    Certificates
  • 25 - 49
    Employees
Company types
Academic/Research
Contract Research Organisation (CRO)
Engineering
Machinery and Equipment Supplier/Manufacturer
Primary activities
Chemical Development
Contract Research Organisation
Laboratory Services
Laboratory, Analytical, Biotechnology Equipment
Supply Chain
Technology

Microinnova Engineering GmbH

  • AT
  • 2015
    On CPHI since
  • 5
    Certificates
  • 25 - 49
    Employees
Company types
Academic/Research
Contract Research Organisation (CRO)
Engineering
Machinery and Equipment Supplier/Manufacturer
Primary activities
Chemical Development
Contract Research Organisation
Laboratory Services
Laboratory, Analytical, Biotechnology Equipment
Supply Chain
Technology

More Products from Microinnova Engineering GmbH (8)

  • Continuous Manufacturing API Plant

    Product Continuous Manufacturing API Plant

    Continuous Manufacturing API Plant
  • Engineering Services for Continuous Manufacturing and for Modular Plants

    Product Engineering Services for Continuous Manufacturing and for Modular Plants

    Basic Engineering - Transform your optimized process into manufacturingMICROINNOVA's engineering team is turning developed continuous chemical laboratory processes into your desired manufacturing plants. Starting with first steps such as piping and instrumentation diagrams (P&ID) and a U...
  • Flow Miniplant

    Product Flow Miniplant

    Bench-top pilot plant for development and small-scale production. The Flow Miniplant is Microinnova’s bench-top flow pilot-plant for the production of quantities between 1 and 100 litres per hour. It bridges the gap between lab-scale flow process development and bulk manufacturing. It’s an indispensable st...
  • GMP Modular Continuos Manufacturing API Plant with Solids

    Product GMP Modular Continuos Manufacturing API Plant with Solids

    We specialize in process development and the design of modular plants and have developed an excellent concept for it. We provide the whole package. From process design, over cost evaluation, to your turnkey plant, optimized and tailored to suit your specific needs. The implementation of a modular...
  • Modular Continuous Manufacturing Crystallization Plant

    Product Modular Continuous Manufacturing Crystallization Plant

    Modular multi-purpose API crytallization plant with PAT and module predictive control.
  • Plant Debottlenecking by Continuous Manufacturing Case Study

    Product Plant Debottlenecking by Continuous Manufacturing Case Study

    Debottlenecking through Continuous Production Capacity increase by means of small skids in the batch plantContinuous production will help you solve the bottlenecks you are currently facing with batch production. The advantages of continuous production are countless, but we have summarized an...
  • Continuous Manufacturing of Formulations in Minutes Instead of Hours

    Product Continuous Manufacturing of Formulations in Minutes Instead of Hours

    Microinnova Engineering GmbH has successfully commissioned two continuous formulation production plants for a European client. The design of the fully automated plant is very compact, which makes it possible to easily transport & install it at a different manufacturing site on the other side of the wor...
  • FlowKiloLab

    Product FlowKiloLab

    Modular plants accelerate time-to-market by using the same infrastructure for development and manufacturing. Production capacities adjust quickly, enabling faster product launches without long construction times. The use of scalable equipment enables a fast scaleup.

    Module Type Package Proto...

Microinnova Engineering GmbH resources (23)

  • Sponsored Content Capacity Boost by Batch-to-Conti Debottlenecking

    Space economy is a typical issue for debottlenecking projects. Since a continuous approach reduces mass and heat transfer distances up to a factor of 100, these solutions can easily be integrated into an existing batch environment. 


     
  • Brochure Who is Microinnova?

    A short presentation highlighting our expertise!
  • Sponsored Content Modular Plants: Speed as the Key Success Factor for Chemical Businesses in the Future

    We expect that speed and flexibility will be success factors for chemical businesses in the future. 
  • Brochure Microinnova Chemistry Portfolio

    PROCESS RESEARCH 

    Development of efficient synthesis routes using the advantages of continuous processing. 

    PROCESS DESIGN

    Decades of experience in process intensification, flow chemistry and continuous processing gives us the ability to investigate the best approach and strategy to put your process into an efficient system.

    CHEMICAL AND TECHNICAL FEASIBILITY

    Inside our flow lab scale plants we have multiple technologies available to develop continuous experimental procedures with the principal objective of showing a reliable mode of operation.

    OPTIMIZATION & PILOT PHASE

    Depending on the inherent characteristics each verified continuous process is optimized. The optimal processing window is determined on scalable equipment to finally deliver a robust continuous system.

  • Sponsored Content Corning and Microinnova Celebrate Opening of Advanced-Flow™ Reactor Qualified Lab

    Corning Incorporated and Microinnova recently celebrated the opening of the Corning® Advanced-Flow™ Reactors (AFR) Application Qualified Lab (AQL) at their facility near Graz. Application qualified labs enable AFR customers to effectively access continuous-flow demonstrations, experimental trials, feasibility testing, and chemical reaction process development.

     
  • Video Modular Plants for Smart Manufacturing

    My name is Katharina and I will show you how continuous modular plants will change chemical processing for a more sustainable future, using modular plug & play plants. We see some issues with batch processing. Sometimes there are concentration spots, the walls are too hot for the molecules. Our philosophy is that all molecules should have the same processing conditions. This we realize by looking at the critical parameters of the chemistry and selecting the right process intensification technology. Furthermore, the space-time-yield can be maximized by a magnitude or more by reducing mass and heat transfer distances, leading to much shorter residence times and compact designs. Since we already have a continuous operating plant in the lab, scale-up becomes much easier. Continuous manufacturing allows for superior quality control due to advanced PAT. Standardized modules enable a quick realization of reduced time to produce and time-to-market. More infos below video!
  • Sponsored Content Intensification Boost for Enzymatic Liquid/Gas Processes by means of Continuous Flow Processing

    O2-dependent biotransformation reactions have proven difficult in fine chemical manufacturing due to the mass transfer limitations of supplying O2 to the enzymatic reaction, hence affecting the level of efficiency achieved. 
     
  • Video 8 Differentiators that make Microinnova Unique

    Microinnova serves its customers as a one-stop-shop from development to manufacturing plants. The following eight differentiators make Microinnova unique. 1. Microinnova focuses on end-to-end continuous manufacturing, dealing with processes in the area of synthesis, work-up and formulation. 
    2. We work with a wide range of different process intensification technologies. We select the best technology for each process. We want to enable uniform process conditions for each molecule. 
    3. We are used to working in regulated environments. We are DIN EN ISO 9001 certified. We can build plants that fulfill typical standards for regulated environments like GMP and ATEX. 
    4. We can handle various conditions. We can process highly viscous materials like melts, suspensions, precipitates and solids in packed or trickle beds. 


    Our other 4 differentiators you can find in the video!
  • Sponsored Content Microinnova Sponsors Award for Outstanding Process Intensification Work Towards CO2 Reduction

    We were honored to have the opportunity to sponsor the 2021 EFCE Excellence Award in Process Intensification.
     
  • Brochure 2nd Generation API Synthesis

    Continuous Manufacturing with Half of the Unit Operations
  • Sponsored Content Microinnova strengthens the field of Digital Processing using Digital Twin Model

    Microinnova strengthens the field of Digital Processing by kicking off the Project “PharmComplete” using Digital Twin, Model-Predictive-Control and PAT strategies.
  • Brochure Process Development & Plant Concept

    ...for a Continuous Hydrogenation Plant

    Environmental & Economic Impact of Solvent-Free Continuous API Manufacture of a Rufinamide Precursor
  • Brochure Flexible Continuous Production

    A continuously operated plant with 4 functional modules was delivered to Evonik Industries in Germany. The plant incorporates advances in process performance and modular "plug-and-play“chemical production technology.
  • Brochure Continuous Modular Crystallization Plants

    Microinnova delivered two modular continuous crystallization plants to the research center CMAC in Scotland and one continuous crystallization plant with an integrated filter-dryer unit to the University of Sheffield. Continuous crystallization, filtration and drying, as an integrated system during continuous manufacturing, is one of the most challenging topics in downstream processing.
  • Brochure Performance Boost for Enzymatic Oxidations by Means of Process Intensification & Continuous Manufacturing

    O₂-dependent biotransformations are promising for chemical synthesis. Their development to the level of efficiency required in fine chemical manufacturing has proven difficult, however, due to thermodynamic and kinetic limitations when supplying O₂ to the enzymatic reaction creating a complex bottleneck on conversion efficiency using batch technology at atmospheric pressure.
  • Brochure In-Situ Bromine Generation for Photochemical Applications in Continuous Manufacturing

    Continuous manufacturing enables options to generate and use hazardous or unstable reagents in a safe manner on manufacturing scale. In this study, we present how in-situ generated bromine can be used for a photochemical application.
  • Brochure 2nd Generation API Synthesis

    Continuous manufacturing with half of the unit operations.
  • Brochure Process Development & Plant Concept

    ...for a continuous hydrogenation plant.
  • Brochure Continuous Modular Crystallization Plants

    Microinnova delivered two modular continuous crystallization plants to the research center CMAC in Scotland and one continuous crystallization plant with an integrated filter-dryer unit to the University of Sheffield. Continuous crystallization, filtration and drying, as an integrated system during continuous manufacturing, is one of the most challenging topics in downstream processing.
  • Brochure Flexible Continuous Production

    A continuously operated plant with 4 functional modules was delivered to Evonik Industries in Germany. The plant incorporates advances in process performance and modular "plug-and-play“ chemical production technology.
  • Brochure Continuous Manufacturing Modular API Plant

    CordenPharma commissioned a modular continuous manufacturing plant from Microinnova Engineering, facilitating improved production capacity.
  • Brochure Debottlenecking by Continuous Production

    Capacity increase by means of small skids in the batch plant

    Continuous production will help you solve the bottlenecks you are currently facing with batch production. The advantages of continuous production are countless, but we have summarized and illustrated them for you to help you make the switch from batch to continuous production!
  • Brochure Continuous Manufacturing of Formulations in Minutes instead of Hours

    Microinnova Engineering GmbH has successfully commissioned two continuous formulation production plants to a European client. The design of the fully automated plant is very compact, which makes it possible to easily transport & install it at a different manufacturing site on the other side of the world.  It possesses an integrated Plug & Play concept, which means that 14 tons per day can be produced. All streams are controlled with precise mass flow meters so no labor intensive pre-weight of substances is needed and instant change of recipe is possible. This provides an easy capacity increase for the client and enables the production of new products.“ 

Frequently Viewed Together

  • Product Pharma Separators

    GEA pharma separator skids aseptic and pure are energizing the industry with two comprehensive and sophisticated separator lines and one revolutionary new multi-bowl solution. These plug & produce pharma separator skids are breaking new ground in ensuring maximum safety, maximum yield and perfect adaptatio...
  • Product KUFill System

    Shanghai tofflon science & technology co. Ltd offers a wide range of filling lines which includes ampoule filling line. Features: it is integrated with washing machine, sterilizing tunnel, filling and sealing machine, it reduces any potential contamination risk from human operation. Contcat us for more...
  • Product HPAPIs ISOLATOR

    • Wide working chamber with a sloping front wall that can be opened upwards• Prismatic Air Lock
    • Static sealsCentrifugal exhauster with inverter
    • Hepa (H14) input filtering unit
    • Double Hepa (H14) output filtering unit
    • Filtered safety valve
    • Pressure gauges
    • Pressure transm...
  • Product MIXER / DISSOLVER

    Our line of stainless steel mixer/dissolvers is suitable for all pharmaceutical application fields, the systems are fully customizable according to user needs.

    There are many combinations, mixing, dissolution and thermoregulation of the product, liquid analysis, weighing and dosing us...
  • Product MC DecJet® Spiral Jet Mills

    The new 4th generation MC DecJet® systems stand for: • Narrow Particle Size Distribution (PSD)
    • Simple and rapid assembly/disassembly • Limited number of components • High yields • Low energy consumption • Sterile manufacturing • PSD scalability with all MC DecJet® models
  • Product Superfine's Vortex mill for Micronization

    Micronization has been for many years a key step in powder processing for special applications where size ranges of 10 microns or less are needed. Nevertheless, the air-jet milling technology has seen very few improvements.



    Limitations of commercial air-jet technologies toda...
  • Product high-pressure hydrogen generator

    TH series high-pressure hydrogen generator is a compact device. With modified proton exchange membrane high pressure electrolysis technology, the generator electrolysis water directly and get pure high pressure hydrogen after steps of purification, booster pump is not required. Operation system and m...
  • Product Dispax Reactor DR

    three-stage high shear inline dispersing machine used for the production of very fine emulsions and suspensions. It can be used (amongst others) for API wet milling and emulsification of pharmaceutical emulsions.
  • Product GMP Bags


    The certified filter bag solutionSEFAR PHARMA GMP Bags is the certified filter bag solution for the pharmaceutical and nutraceutical  industry. The design has been developed to avoid possible contamination from staple fibers coming from the needle felt.

    An ePTFE microporous mem...
  • Product Pervaporation Technology

    Pervaporation is a liquid/liquid separation process using a selective and dense membrane. 

    By creating a vacuum or introducing a flow of purge gas on one side of a dense membrane, volatile compounds in the liquid present on the other side will selectively diffuse through the membrane....
  • Product Capacity 6000L Glass Lined Reactor with Motor, Agitator, Mechanical Seal...

    1. Application:
    Capacity 6000L Glass Lined Reactor With Motor,Agitator,Mechanical Seal Etc. is an ideal material for anti acid and alkali corrosion and its surface is very easy to Polish and no contamination to mediums. It's widely used in Petrochemicals, light 
    industry, pharmaceut...
  • Product PWD commercial filter/dryer

    PWD pilot filter/dryer is designed to fit commercial scale operations with the functionalities of isolation (solid/liquid separation), washing and drying of specialty compounds (e.g. APIs, fine chemicals etc.). The design of the PWD commercial filter/dryer follows the same design as PWD pilot filter/dr...
  • Product Microfluidizer technology

    By using microfluidization technology process, Skyepharma provides solution to increase bioavailabity of poorly soluble APIs (micro and nanoparticule). It is also an interesting technology for micro and nano emulsion manufacturing.
  • Product Vibratory Conveyors, mixers & blenders, secondary packaging, dosing unit...

    Over the past decade, Kiron Food Processing Technologies (KFPT) has played a vital role in finding innovative solutions by representation and connecting the best food processing systems manufacturers from around the world to India's flourishing processed food Industry. With our forte in broad-spectrum ...
  • Product Automatic & Semiautomatic R&D Reactor, Condenser, Receiver with Heating ...

    1.     Automated Efficiency: Our Automatic R&D Reactor System streamlines operations, allowing for precise control and automation of crucial parameters, ensuring reproducibility in experiments.

    2.     Semiautomatic Flexibility: For those seekin...
  • Product SEP-40K production scale phase separator

    Zaiput Flow Technologies' patented separator (SEP-40K) provides continuous separation of an immiscible phase (liquid-liquid or gas-liquid) by leveraging differences in wetting properties of the liquids onto porous membranes.
    The device can achieve a throughput of 40 Lt/min
  • Product Used/Unused Process Equipment

    IPP offers a unique option for companies by specializing in the buying and selling of complete plants, process lines, and equipment across the globe. We own over 15,000 pieces of good used, unused and reglassed process equipment built by hundreds of different OEMS that are available for immediate...
  • Product Reactor/ Hydrogenerator

    Reactor with all type of agitators including gas induction /Hydrogenator. With insulation and as per cGMP.
  • Product Pressure Spray Dryer

    Pharmaceutical-grade Excellence:Our Pressure Spray Dryer is crafted for the pharmaceutical sector, ensuring drug stability and efficacy with unmatched moisture control.

    Key Features:    • Optimized Drying: Rapid, consistent drying via pressurized conditions. • Particle Precision: Supe...
  • Product Contained vacuum drying

    Contamination is unacceptable and the cGMP Nauta vacuum dryer is a proven technology for excellent cleaning (CIP) and sterilising (SIP) in place. It has a closed process vessel with a cover and filter made out of one piece. This eliminates dead spots and offers validated automatic SIP/CIP. There are no oil...
  • Product Centrifuge

    An industrial centrifuge is a machine that uses centrifugal force to separate components of a mixture based on their density or particle size. It consists of a rotating drum or bowl that contains the mixture to be separated, and the rotation creates a centrifugal force that pushes the components toward...
  • Product GMP Modular Continuos Manufacturing API Plant with Solids

    We specialize in process development and the design of modular plants and have developed an excellent concept for it. We provide the whole package. From process design, over cost evaluation, to your turnkey plant, optimized and tailored to suit your specific needs. The implementation of a modular...
  • Product ULTRASAFE Containment Isolators

    When containment has to be both complete and completely reliable, ULTRASAFE is the optimum solution. Our high containment equipment provides advanced performance levels for both API and HPAPI, backed by a service that's ultra focused on your needs.
  • Product REACTOR SYSTEMS BASED ON GLASS-LINED REACTORS WITH JACKET AND GLASS AUXI...

    • Operating volume of the glass-lined reactor: from 50 to 5000 l • Volume of glass measuring vessels with a jacket and an agitator from 15 to 100 l • Volume of glass measuring vessels without a jacket from 10 to 300 l • Mounting of glass components on a stainless-steel scaffolding. • Scaffolding...
  • Product Spray Dryer

    GEA Niro pharmaceutical spray dryers from R&D to large production scale. Come and discuss your Pharma Spray Drying project with us or learn more about our pharma spray drying technology. Welcome!
  • Product Continuous Microreaction Hydrogenation Platform

    H-Flow series is built on the patented microreaction hydrogenation technology of Tsinghua University, which mixes highly pure hydrogen with continuously flowing reactants in a micropacked column loaded with catalysts and reacts. Combining automatic control of the whole process, inline real time measurem...
  • Product Glove Box Isolator

    If the isolation technology in recent years is playing a role of growing importance, this is mainly due to the well-established trend, especially in the chemical and pharmaceutical field, to treat substance and / or develop molecules with high activity and toxicity (API – HAPI). This in conj...
  • Product BIN / DRUM LINE

    Our line of Stainless Steel BIN and DRUM are suitable for all handling / manipulation of API and OSD, powders, liquids and viscous in pharmaceutical processes.

    Made on standard models and / or according to customer / plant construction spefications, they are durable, solid ans reliable. q...
  • Product Agigated Nutsche Filter/Dryer (ANF/ANFD)

    MAGTECH Agitated Nutsche Filter Dryer is high-quality equipment designed for solid-liquid separation processes, by filtration under pressure and vacuum drying, for the pharmaceutical, chemical, fine chemical and food industries. Magtech Design and manufacture as per the standard design.
  • Product Centrifugal Spray Dryer

    Centrifugal Spray Dryer is tailored for the pharmaceutical sector, transforming liquid solutions into powders or granules via atomization and drying.
    Features:    • Efficiency: Centrifugal atomization ensures rapid drying and uniform particle size. • Flexibility: Adaptable for heat-sensit...
  • Product Glass Lined Reactor Stainless Steel Cladded for Pharmacy and Foodstuff

    1. Application:
    Glass lined reactor stainless steel cladded For Pharmacy and Foodstuff is an ideal material for anti acid and alkali corrosion and its surface is very easy to Polish and no contamination to mediums. It's widely used in Petrochemicals, light industry, pharmaceuticals, pes...
  • Product Cgmp lab freeze dryers

    Shanghai tofflon science & technology co. Ltd offers a wide range of auto loading systems which includes cgmp lab freeze dryers. Features: it is cgmp designed, cylindrical process chamber and external condenser located behind freeze-drying chamber, air cooling and water cooling compressor for option. Contc...
  • Product Glass Lined Reactor for Chemical Industry

    1. Application:
    Jacket Heating Glass Lined Reactor for Chemical Industry is an ideal material for anti acid and alkali corrosion and its surface is very easy to Polish and no contamination to mediums. It's widely used in Petrochemicals, light industry, pharmaceuticals, pesticide, f...
  • Product Continuous Crystallization Technology

    Production equipment for a controlled crystallization process.

    Through the use of small diameter capillaries, the crystallization tool of Secoya is able to master supersaturation conditions and control the nucleation process. By precisely selecting parameters, the nucleation rate can be adjusted to ...
  • Product REATORG TECHNOLOGIES ™ STANDARD JACKETED GLASS REACTORS

    • Working volume: 15, 30, 50 and 100 l • Scope of supply: measuring vessel, reflux condenser, receiving vessel • Temperature range from -40 ° С to + 180 ° С • Pressure from -0.98 to +0.5 bar • Borosilicate glass 3.3 made in Europe (glass composition certificate for validation) • Partially detach...
  • Product Closed Loop Spray Dryer

    The Closed Circuit Spray Dryer by RETCL Process is engineered for the pharmaceutical sector, designed for drying special solvents and materials. Unlike conventional spray dryers using air, this utilizes a nitrogen loop, enhancing purity and safety.
    Operating Principle:Nitrogen is heated and circulated t...
  • Product Centrifuge

    Sefar filter solutions for centrifugesCentrifuges operate on the principle of centrifugal force and a filter cloth to separate solids from liquids. High rotational speed provides high centrifugal force that allows the suspended solid in the feed to settle on the surface of a filter media. Washing processes...
  • Product UNIVERSAL SYNTHESIS UNIT REATORG TECHNOLOGIES™ BASED ON GLASS REACTOR

    • Borosilicate glass 3.3 European production (certificate for glass composition for validation) • Scaffolding: 304L stainless steel • Scaffolding fasteners: 321 alloy steel • Working volume from 15 to 100 liters for vessels with a jacket and up to 300 liters for vessels without a jacket. • Any ...
  • Product API Pharmaceutical Plants and Equipment - Used Equipment and Complete Si...

    IPP has available complete pharmaceutical plants that can be operated in place as well as relocation.

    We have recently acquired pharmaceutical systems in both API and Formulation that can be moved to your plant site saving your projects 50-60% of the equipment value versus new. You can also save...
  • Product PWD pilot filter/dryer

    PWD pilot filter/dryer is designed to fit pilot scale testing with the functionalities of isolation (solid/liquid separation), washing and drying of specialty compounds (e.g. APIs, fine chemicals etc.). The filter has a filtration area of ca. 0.33m2 and a maximum chamber capacity of ca. 140liters, howe...
  • Product Engineering Services for Continuous Manufacturing and for Modular Plants

    Basic Engineering - Transform your optimized process into manufacturingMICROINNOVA's engineering team is turning developed continuous chemical laboratory processes into your desired manufacturing plants. Starting with first steps such as piping and instrumentation diagrams (P&ID) and a U...
  • Product PWD laboratory filter/dryer

    PWD laboratory filter/dryer is designed to fit laboratory scale testing with the functionalities of isolation (solid/liquid separation), washing and drying of specialty compounds (e.g. APIs, fine chemicals etc.). The filter has a filtration area of ca. 0.015m2 and a maximum chamber capacity of ca. 5lit...
  • Product Modular Continuous Manufacturing Crystallization Plant

    Modular multi-purpose API crytallization plant with PAT and module predictive control.
  • Product Jet Mill

    Designed to achieve particularly high fineness, this mill offers the possibility to obtain particle sizes even below 5 microns. The working principle does not contemplate the use of grinding bodies, since the reduction takes place exclusively by collision between the particles of product, fe...
  • Product Continuous Manufacturing API Plant

    Continuous Manufacturing API Plant
  • Product Fluid Bed Dryer

    Sefar Filter Solutions for Fluid Bed DryerFluidized bed technology is used in many applications such as the formulation process in the pharmaceutical industry or the production of fine chemical powders by mixing, agglomeration, granulation, sizing, drying, coating or micronizing.

    Over the last 2...
  • Product Flow Miniplant

    Bench-top pilot plant for development and small-scale production. The Flow Miniplant is Microinnova's bench-top flow pilot-plant for the production of quantities between 1 and 100 litres per hour. It bridges the gap between lab-scale flow process development and bulk manufacturing. It's an indispensable st...