KOCO® - The first semi-continuous coater

L. B. Bohle Gmbh offers a wide range of process machines which includes vma - single pot granulator for pharmaceutical applications. It is a granulating and drying system specifically optimized for pharmaceutical applications. The flexible machine is state-of-the-art, and exceeds current gmp requirements w...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle fluid bed system bfs - bohle uni cone buc ®. It is the productive, practical and precise alternative to conventional wurster processing. it features a broad range of extension options for bottom tangential spray granulation as we...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle film coater bfc. Benefits: it provides homogeneous mixing due to patented spirals, simple and quick discharging by reversing the direction of rotation and has a high sophisticated control system. Contact us for more information.

L. B. Bohle Gmbh offers a wide range of process machines which includes compact granulation system. It covers process, cleaning, control and explosion protection as well as qualification. Benefits: gma granulator ® and bohle fluid bed system bfs built into the wall right next to each other, small footprint...

Bohle is the world’s leading manufacturer of blenders. The high efficiency of the Bohle blending systems is based on the revolutionary and patented counter-current process principle.

The range of Bohle blending systems shows the flexibility of our engineering and manufacturing departments. B...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle film coater bfc tripan. It is a bohle film coater with a suspension supply via a single pump head. tripan can be operated with three pans for batch sizes of 7 to 75 liters. Benefits: it provides easy cleaning, has a suspension su...

The Granumator ® GMA is a granultion system specifically optimized for pharmaceutical applications. The impeller is designed for high shear and compression, ensuring effective granulation. The chopper prevents excessive granule growth and distributes the granulating liquid within the product.
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L. B. Bohle Gmbh offers a wide range of process machines which includes bohle film coater bfc 5 - stand-alone unit. It is is a stand-alone unit. The entire air technique as well as electrical and control technique is integrated in the system. Benefits: it can be operated with one of two differtent pan size...

The Bohle Tablet Checker is used for a mechanical check of the thickness of sugar-coated or film-coated pills, capsules and tablets. The feeding hopper is filled with tablets to be tested. From there, a vibrator system guides the tablets to the rotating sorting discs.

Three different gro...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle turbo sieve bts. Benefits: it has an innovative impeller design, mobile, height adjustable, flexible, has production capacities of 2-3 tons/hour and conical perforated screens of different mesh sizes. Contact us for more informat...

L. B. Bohle Gmbh offers a wide range of process machines which includes bohle turbo mill btm. Benefits: it is easy to operate, modular and compact, integrated moblie lifting column, has automnatic rotary valve protects against overfilling and rotor with hammer and knife sides. Contact us for more information.

The L.B. Bohle Pharma Universal Cleaning System guarantees best cleaning results. The economical container washing system PUR has a compact design, but with the major functionality of an expensive WASH-CABIN. It can be easily used for various container sizes and shapes. It comprises a height adju...

Continuous wet granulation and drying have long been a hot topic in pharmaceutical research and development (R&D) and industry. However, there is no truly continuous fluid-bed dryer on the market that is suitable for a long process time and that meets the quality requirements described in the present article. This article outlines the experimental testing on a new R&D system (QbCon® 1) for truly continuous granulation and drying. Special attention is paid to the dryer and the resulting granules.
The results show that very narrow and reproducible residence time distributions are achieved in the dryer, which leads to uniform drying of the granules of different size classes. The process delivers consistent quality regarding moisture and particle size of the granules over several hours. When changing the conveying speed of the granules in the dryer while maintaining all other parameters, it was possible to describe the limits for a fixed process/formulation combination, ...