Generic Antibodies

We deliver responsive QC analysis for complex biologic products from our cGMP laboratories. Our scientists develop and validate methods or perform technology transfer of a sponsor's method for a wide range of analytical methods required for batch release testing. We also routinely carry out testing to Phar...

• Pegfilgrastim (Filed with EMA) • Filgrastim (Filed with EMA) • Trastuzumab (Filed with EMA, MHRA, Received recommendation for marketing authorization in India) • Bevacizumab (Filed with MHRA) • Omalizumab (Global PhIII ongoing) • Denosumab (Global PhIII ongoing) • Ranibizumab (Global PhIII ongoing...

FCMES - AM® (Full Coverage Mammalian Expression System) is Biointron's proprietary platform for affinity maturation. Each amino acid in the CDR region will be mutated to the other 18 amino acids (except Cysteine) with equal ratios. The clones will be expressed in a mammalian system and an ELISA binding ass...

Monoclonal antibody therapeutics: We continually invest in advanced analytical instrumentation that allows us to deliver mAb analytical data with the highest degree of sensitivity, accuracy and resolution. Our experience spans recombinant monoclonal antibodies and related products such as biosimilars, ...

We design bespoke analytical programmes that ensure that the relevant quality attributes for your drug substance or product are evaluated to support your manufacturing process changes. We select analytics referenced by the ICH Q6B to examine the product's structural features (primary, secondary and&nb...

Intertek offers wide range of pharmaceutical services which includes post-translational modifications. It belongs to biopharmaceutical protein analysis services category. It includes deamidation, glycosylation, glycylation, phosphorylation, acetylation , alkylation, sulfation, etc.

Expression systems utilizing mammalian cells for recombinant protein manufacture introduces proper protein folding, post-translational modifications, and protein assembly, which are important for producing proteins of complete biological activity, and thus is in high demand in the therapeutic development a...

These packages are designed to offer cost-effective, time-saving solutions to meet small-scale rush needs in as fast as 8 days, with a sizable production capability for more than 5K samples.

Now adding RushMab-Gene! With only 4 days, we can have 100ug transfection-grade expr...

Biointron's CHOKTBN cell line, licensed from ECACC (CHO-K1), is suspension-adapted in basic CD media. The cell line can be sublicensed for commercial use, and it meets the requirements for registration in both China and US.

Highlights: • Worldwide Sublicense • No Royalty Fee • Perp...

Biointron provides a stable cell line development service for bioproduction purposes. Our stable cell line service, based on ECACC licensed CHO-K1 cells, aims to provide a high-yield guaranteed and speedy timeline to meet your downstream applications.

Highlights: • High-Yield: >5 ...

Biointron's fucose-free host cell CHOK1BN-Fut8KO can be used for industrial production following antibody characterization and functional verification. Compared to the unmodified CHOK1BN cell line, the antibody produced by the modified cell line not only achieves afucosylation but also maintains consistenc...

The antibody sequence is crucial for patent applications (distinguish your antibody from others), recombinant antibody expression, antibody engineering (humanization & affinity maturation), and more. Biointron offers a high-quality hybridoma sequencing service, for the sequencing of variable regions of...

Recombinant antibody technologies are rapidly becoming available and showing considerable clinical success. However, murine monoclonal antibodies may induce immunogenic responses, potentially limiting their application for humans. Humanized antibodies can overcome these problems and are considered to be a ...

Biointron offers a high-throughput, fully integrated platform for accelerating antibody discovery. Biointron's high-throughput single B cell screening platform can screen 2*10^6 plasma B-cells from immunized animals. Antigen specific antibody-secreting cells can be isolated. It allows the detection of pote...

Producing therapeutic antibodies or proteins in large quantities is required for many applications, including in vitro studies, in vivo animal studies, and pre-clinical trials. Biointron' s large-scale Producing services offers scaled-up production of recombinant antibodies/ proteins from hundreds of milli...

Bispecific antibodies represent a key component of the next-generation of antibody therapy. Bispecific antibodies can target more than two different antigens at the same time. For instance, they can simultaneously bind tumor cell receptors while recruiting cytotoxic immune cells.Biointron has expressed tho...

Biointron's high-throughput antibody production provides the most cost-effective option for recombinant antibodies, where you may choose to deliver either supernatant or purified antibodies (ug to gram level). From gene synthesis to purified antibodies (IgG, scFv, VHH, etc.), it takes as fast as 2 weeks. A...

Biointron’s catalog products for in vivo research can be found at Abinvivo, where we have a wide range of: • Benchmark Positive Antibodies • Isotype Negative Antibodies • Anti-Mouse Antibodies • Bispecific Antibodies • Antibody-Drug Conjugates • Dilution Buffers