Benzyl Alcohol

Benzyl Alcohol BP
C7H8O ... 108.1 ... 100-51-6
Benzyl Alcohol BP

DEFINITION
Phenylmethanol
Content
98.0 per cent to 100.5 per cent.

CHARACTERS
Appearance
Clear, colourless, oily liquid.
Solubility
Soluble in water, miscible with ethanol (96 per cent) and with fatty and essential oils.
Relative density
1.043 to 1.049.

IDENTIFICATION
Infrared absorption spectrophotometry.
Comparison: benzyl alcohol  CRS.

TESTS
Appearance of solution
Shake 2.0 ml with 60 ml of water. It dissolves completely. The solution is clear and colourless.
Acidity
To 10 ml add 10 ml of ethanol (96 per cent) and 1 ml of phenolphthalein solution.  Not more than 1 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator to pink.
Refractive index
1.538 to 1.541.
Peroxide value
Maximum 5.
Related substances
Gas chromatography to pass the tests

Benzyl Alcohol USP NF
C7H8O 108.14
Benzenemethanol.
Benzyl alcohol USP [100-51-6].

Benzyl Alcohol contains not less than 98.0 percent and not more than 100.5 percent of C7H8O.

Labeling— Where Benzyl Alcohol is intended for use in the manufacture of injectable dosage forms, it is so labeled.

Clarity of solution—
Test solution— Dissolve 2.0 g of Benzyl Alcohol in 60 mL of water, and mix.
To pass the test as per monograph
The Test solution shows the same clarity as that of water, or its opalescence is not more pronounced than that of Reference suspension.
Color of solution—
Test solution— Use the Test solution prepared in the test for Clarity of solution.
To pass the test as per monograph
Test solution has the color of water.
Identification— Infrared Absorption 197F , on un-dried specimen.
Peroxide value: not more than 5.
Refractive index: between 1.538 and 1.541 at 20.
Acidity— Neutralize 50 mL of alcohol containing 1 mL of phenolphthalein TS with 0.10 N sodium hydroxide. Dissolve 10 mL of Benzyl Alcohol in 10 mL of the neutralized alcohol, and titrate with 0.10 N sodium hydroxide to the first appearance of a pink color that persists for not less than 30 seconds: not more than 1.0 mL is consumed.
Limit of nonvolatile residue— [NOTE—Ensure that the Benzyl Alcohol to be examined complies with the test for Peroxide value before performing this test.] Evaporate 10.0 g of Benzyl Alcohol on a water bath to dryness, and dry the residue at 105 for 1 hour. Cool in a desiccator, and weigh. The residue weighs not more than 5 mg: not more than 0.05% of nonvolatile residue is found.
Related compounds—
Test solution— Use the Benzyl Alcohol specimen under examination.
To pass the test as per monograph

Benzyl Alcohol ACS Analytical Reagent

Benzenemethanol C6H5CH2OH
Formula Wt 108.14
CAS Number 100-51-6

REQUIREMENTS
Assay:
99.0% C6H5CH2OH

MAXIMUM ALLOWABLE
Color (APHA): 20
Residue after ignition: 0.005%
Acetophenone (C6H5COCH3): 0.02%
Benzaldehyde (C6H5CHO): 0.01%