Suppocire BM Pellets

Precirol® ATO 5 (glyceryl palmitostearate) is a glyceride with an intermediate melting point used as lubricant and flow aid in powder blends for capsule filling and as a coating agent for taste masking.

Gattefosse S.A offers a wide range of products which includes Sedefos™ 75. It belongs to emulsifiers category. It is recommended for anhydrous emulsions for hydrosensitive actives requiring PEGs or glycerine as hydrophilic phase, emulsions containing a high concentration of alcohol or oily phase, acidic ac...

Suppocire® AGP Pellets is hard fat suppository base with emulsifier to improve dispersion of hydrophilic APIs, recommended for formulation of glycerin suppositories.

Suppocire® AM Pellets is a hard fat suppository base that provides excellent chemical stability with acidic APIs and high crystallization rate.
A versatile base with precedence of use with a wide range of APIs.

Suppocire® AP Pellets is hard fat suppository base comprising polyoxylglyceride esters to enhance drug solubility and bioavailability.

Suppocire® AS2 Pellets is a hard fat suppository base with modified monoglyceride content recommended for hydrophilic APIs requiring fast release.

Suppocire® BS2X Pellets is a hard fat suppository base containing polysorbate additive to improve dispersion of hydrophilic APIs in aqueous solutions or hydroalcoholic extracts.

Suppocire® NAI 25 A Pellets is a hard fat suppository base optimized for the formulation of analgesics and antipyretics. Confers high mechanical resistance and yields harder suppository units.

Suppocire® NB Pellets is a hard fat suppository base with intermediate melting point. Confers high mechanical resistance and yields harder suppository units.

Tefose® 1500 (mixture of PEG-6 stearate and PEG-32 stearate) is a  nonionic oil-in-water emulsifier for topical formulations that provides high stability in topical fluid lotions and light emulsions over a wide pH range.

Tefose® 63  (mixture of PEG-6 stearate and ethylene glycol palmitostearate and PEG-32 stearate) is a nonionic oil-in-water emulsifier for topical formulations.  It delivers high stability for a wide range of APIs in emulsions. Widely used in vaginal creams due to high mucosal tolerance.
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Transcutol® HP (diethylene glycol monoethyl ether) is the highest-purity grade solvent and solubilizer for solubility and bioavailability enhancement for oral and alternative routes (parenteral, nasal, ophthalmic formulations).

Discover Gelucire® 59/14, an add-on in Gattefossé Gelucire® range, for oral bioavailability enhancement

Selecting best excipient

Discover Labrafac™ MC60, glycerol monocaprylocaprate, an oral bioavailability enhancer.

This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. Patient adherence to skin treatments Bi-gels: formulating new topical drugs Emulfree® Duo, a ready-to-use excipient designed to make bi-gels Case studies

Discover our brand new excipient Emulfree® Duo, a ready-to-use stabilizing agent, enabler of bi-gel, an emerging topical dosage form.

This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. This session explores: Using Lipid-based formulations to address oral bioavailability issues Labrafac™ MC60, glycerol monocaprylocaprate, Gattefossé new bioehancer Case study: step-by-step development of a lipid-based formulation of dutasteride with Labrafac™ MC60 Gattefossé technical expertise

Many drugs exhibit poor solubility and/or permeability leading to weak oral bioavailability. To overcome these issues, different technologies have been developed. Among them, lipid-based formulation (LBF) is an option worth considering as it can be used from the very beginning of drug development to product, reducing time to market.