Gelucire® 59/14, solid surfactant for oral bioavailability enhancement
Discover Gelucire® 59/14, an add-on in Gattefossé Gelucire® range, for oral bioavailability enhancement
Gattefossé widens its range of functional excipients for oral bioavailability enhancement with a new grade of Gelucire®: Gelucire® 59/14, a mixture of lauroyl PEG-32 glycerides EP/NF and PEG 6000 EP/NF.
Gelucire® 59/14 is
a self-emulsifying excipient used for oral bioavailability enhancement of
poorly water-soluble drugs, owing to its high solubilizing capacity. Gelucire®
59/14 is supplied in pellets, which makes it easy to handle and an interesting
add-on to our Gelucire® range.
Gelucire® 59/14 is a self-emulsifying system: upon contact
with aqueous or digestive media it spontaneously forms a fine dispersion.
The different components self-assemble as a function of their affinity
for water, resulting in the formation of micelles, wherein the drug is
solubilized. This mechanism contributes to an increased absorption and hence
bioavailabiity of drugs.
For more information on our offer for lipid-based formulations,
download our brochure.
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