RetaLac - co-processed Excipient

RetaLac® is a co-processed spray agglomerate consisting of equal parts of alpha-Lactose monohydrate [Ph. Eur. / USP-NF / JP] and Hypromellose [Ph. Eur. / USP-NF / JP], calculated on a dry basis. The product is a white / off-white, odourless powder. As the two components cannot be separated by mechanical methods, segregation during processing is not possible. The SEM picture illustrates that RetaLac® granules have a coarse texture with an highly structured surface (figure 1). RetaLac® is partially soluble in cold water, the resultant liquid is clear or slightly turbid with a viscosity dependent upon concentration. In comparison with pure HPMC the wettability of RetaLac® is significantly improved.