Probiotical S.p.A.

  • Company Profile
  • Probiotical
  • Probiotical
About Probiotical S.p.A.

Probiotical was born in 1985 and has ever since driven the innovation in the probiotics industry. Daughter company of ALCE Microbiologic Laboratory, Italian leader in the production of lactic acid bacteria for the dairy industry, it is the first plant worldwide designed exclusively for the production of probiotic microorganisms for the pharmaceutical and nutraceutical industries. Probiotical has a very high quality positioning and is partner of globally leading pharmaceutical companies.

We offer a very broad portfolio of scientifically-backed pr...

  • IT
  • 2017
    On CPHI since
  • 50 - 99
    Employees
Company types
Academic/Research
Manufacturer/Innovator
Contact info
Meet us at

CPHI Frankfurt 2025

Messe, Frankfurt
28 Oct 2025 - 30 Oct 2025

Products from Probiotical S.p.A. (22)

  • Bifizen® Range

    Product Bifizen® Range

    BIFIZEN® is a probiotic blend to reduce depressive mood state, fatigue and anger and improve the quality of sleep and of mood state in healthy individuals.
  • Bifizen®

    Product Bifizen®

    GABA Production
    stimulation
    Mood improvement

  • Bifizen®Kids

    Product Bifizen®Kids

    BIFIZEN® Kids is a natural, probiotic-based solution for Kids mental and cognitive
    health.
  • Bifidigest®

    Product Bifidigest®

    Bifidigest® is a probiotic product specifically designed for rebalancing intestinal microflora and support healthy digestion.

  • Bifiasthm®

    Product Bifiasthm®

    Bifiasthm is a probiotic product proposed for children with asthma, in order to prevent asthmatic crises and support the balance of the immune system reactivitity. Bifiasthm is based on B. breve B632 and L. salivarius LS01, two strains with immunomodulatory activity targeted for allergic asthmatic subj...
  • Bifimmun®

    Product Bifimmun®

    Bifimmun is a synbiotic food supplement for the immune system, based on 3 different strains and prebiotic fiber FOS (B. lactis BS01, L. plantarum LP02, L. rhamnosus LR04). Bifimmun has provoked  in a clinical trial involving 471 adults a significant reduction in prevalence, severity and duration o...
  • Bifislim®Junior

    Product Bifislim®Junior

    BIFISLIM® Junior can help re-establish metabolic homeostasis and reduce chronic
    inflammation in obese children.


  • Celiaflora®Adults

    Product Celiaflora®Adults

    CELIAFLORA™ Adults is a probiotic food supplement specifically designed to help reduce intestinal inflammation, gut dysbiosis and dysregulated intestinal permeability in subjects suffering from gluten sensitivty.
  • Bifizen®Age Well

    Product Bifizen®Age Well

    BIFIZEN® Age Well is a natural, probiotic-based solution against age-related cognitive decline and to improve memory, focus and attention.
  • Bififiber®

    Product Bififiber®

    Bififiber is natural synbiotic based on the association of B. lactis BS01 and prebiotic fiber FOS with clinically-proven efficacy on 110 subjects with evacuation disorders. Bififiber is able to significantly alleviate symptoms of constipation, increase the number of weekly evacuatio...
  • Bifisport®

    Product Bifisport®

    Bifisport is an innovative solution for athletes to enhance performance throughout training and competition. While intense training causes muscle inflammation and performance decrements, this association of St. thermophilus FP4 and B. breve BR03 demonstrated clinically, in athletes,...
  • Floratopic®

    Product Floratopic®

    Floratopic is an advanced, therapeutic probiotic product based on L. salivarius LS01 and clinically studied, in children and in adults, for the improvement of atopic dermatitis symptoms (measured by SCORAD). Importantly, LS01 is able to orientate the immune response in order to rees...

Probiotical S.p.A. Resources (6)

  • News Probiotical white paper_immune defenses high definition

    An effective immune system is your best defense, and the right probiotics can help! The COVID-19 global crisis has led to a peak in demand for products able to stimulate immunity. Given the well-established importance of the microbiota in immune health, Chinese authorities have emitted in February an official recommendation for the use of probiotics in the treatment of patients with severe COVID-19 infection (1, 2).
  • Video Bifizen Range

    Bifizen is a probiotic combination of 4 strains selected for complementary mechanisms of action to benefit the gut-brain axis: L. fermentum LF16, L. rhamnosus LR06, B. longum 04 and L. plantarum LP01. Bifizen supplementation for 6 weeks in healthy students showed significant benefits in depressive mood, anger, fatigue and quality of sleep. The product is now declined as a range for mental well-being for the whole family.
  • Brochure Lactobacillus rhamnosus GG, API

    L. rhamnosus GG (ATCC53103) is the most studied probiotic strains worldwide with over 1000 publications, and especially recommended in pediatric diarrhea management and antibiotic-associated diarrhea but also studied across a number of other functionalities. We propose this strain in high quality, allergen-free, high concentration and as Active Pharmaceutical Ingredient, backed by the Drug Master File, for your pharmaceutical development.
  • Brochure Bifiasthm, prevent asthmatic crises and support the immune system

    Bifiasthm is a probiotic product proposed for children with asthma, in order to prevent asthmatic crises and support the balance of the immune system reactivitity. Bifiasthm is based on two strains with immunomodulatory activity targeted for allergic asthmatic subjects. A placebo-controlled clinical trial pending publication in 2020 and involving 500 asthmatic children showed that Bifiasthm was able to reduce significantly the episodes of asthma.
  • Brochure Bifivir, immune defenses

    Bifivir is a synbiotic supplement for the immune system, based on 5 strains and prebiotic fiber. Bifivir has led, in several clinical trials involving in total nearly 900 adults, to a significant reduction in prevalence, severity and duration of respiratory tract infections and influenza-like illnesses, including flu.
  • Brochure Bifizen, gut-brain axis

    Bifizen is a probiotic combination of 4 strains selected for complementary mechanisms of action to benefit the gut-brain axis, which showed significant benefits in depressive mood, anger, fatigue and quality of sleep. The product is now offered as a range of 5 products for mental well-being for the whole family.