Orlobin (Amikacin sulfate500 mg/2ml solution for injection/infusion)

Therapeutic Indications

Amikacin sulfate is an aminoglycoside antibiotic which is active against a broad spectrum of Gram-negative organisms, including Pseudomonas spp, Escherichia coli, indole-positive and indole-negative Proteus spp, Klebsiella-Enterobacter-Serratia spp, Salmonella, Shigella, Minea-Herellae, Citrobacter freundii and Providencia spp.

Many strains of these gram-negative organisms resistant to gentamicin and tobramycin may show sensitivity to amikacin in vitro. The principal Gram-positive organism sensitive to amikacin is Staphylococcus aureus, including methicillin-resistant strains. Amikacin has some activity against other Gram-positive organisms including certain strains of Streptococcus pyogenes, Enterococci and Diplococcus pneumoniae.

Orlobin is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It may also be indicated for the treatment of known or suspected staphylococcal disease. Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Advantages

Extended efficacy over a broad spectrum of clinical indications

The aminoglycoside of choice in infections of unknown etiology including:

- Psedomonas infections

- Infections by other aerobic Gram-negative bacteria

- Enterobacter and staphylococci infections

Orlobin treatment offers:

- Excellent microbial response

- High antimicrobial efficacy

- Low MIC and high levels in blood and tissues

Available in packages of 1 vial

For more information please consult the detailed patient Summary Product Characteristics