NICE Rejects Ovarian Cancer Treatment
NICE explains that it is not sure that trabectedin extends patients' lives for longer than the most routinely used treatments.
The National Institute for Health and Clinical Excellence (NICE), based in UK, has rejected trabectedin (Yondelis) in combination with pegylated liposomal doxorubicin (PLDH) as a treatment for ovarian cancer.
In a draft guidance issued on Friday, NICE raised concerns over how well the treatment would work compared with the most commonly-used treatments.
NICE Chief Executive Sir Andrew Dillion said, "According to clinical experts, retreatment with platinum-based chemotherapy is the preferred option for relapsed platinum-sensitive ovarian cancer. "The manufacturer of trabectedin [PharmaMar] did not submit any evidence comparing trabectedin with platinum-based chemotherapy, comparing it instead with drug regimen
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