Impurity purification and identification

Impurity purification and identification
Product Description

Purification of metabolites and impurities and structural identification by cryoprobe NMR spectroscopy with certificates of analysis.

Hypha Discovery Ltd

  • GB
  • 2024
    On CPHI since
  • 25 - 49
    Employees
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Contract Service
Start-up
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Laboratory Services
Natural Extracts

Hypha Discovery Ltd

  • GB
  • 2024
    On CPHI since
  • 25 - 49
    Employees
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Contract Service
Start-up
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Laboratory Services
Natural Extracts

More Products from Hypha Discovery Ltd (6)

  • Custom metabolite synthesis

    Product Custom metabolite synthesis

    Scalable synthesis of phase I and phase II metabolites of drugs and agrochemicals using biotransformation and chemical synthesis.
  • Custom natural products

    Product Custom natural products

    Hypha scientists are experts in the discovery, fermentation, purification and structure elucidation of microbial natural products and can support any aspects of projects in these areas.
  • Metabolite synthesis kits

    Product Metabolite synthesis kits

    Scalable recombinant enzyme kit to make CYP and other Phase I metabolites: Screening kits and scale up kits of resupplied individual enzymes available for purchase.
  • PolyCYPs kits for the synthesis of oxidized metabolites

    Product PolyCYPs kits for the synthesis of oxidized metabolites

    PolyCYPs Metabolite KitsEasy-to-use in-vitro enzyme system for generation of CYP, AO and FMO derived metabolites of drugs, agrochemicals and other small molecules


    PolyCYPs+ metabolite kits are used by scientists in pharmaceutical and agrochemical companies to screen for and scale-up human and ot...
  • Drug substance impurity purification and identification

    Product Drug substance impurity purification and identification

    Hypha are experts in purification and identification of minor (sub mg) drug substance impurities.Cryoprobe NMR is used to elucidate structures, even when <100ug of impurity is available.
    A range of late-stage biocatalysis and chemistry techniques is available to screen for the production of the impur...
  • Tacrolimus M-II metabolite_31-DeOMe

    Product Tacrolimus M-II metabolite_31-DeOMe

    Tacrolimus metabolite standard

Hypha Discovery Ltd resources (14)

Frequently Viewed Together

  • Product PolyCYPs kits for the synthesis of oxidized metabolites

    PolyCYPs Metabolite KitsEasy-to-use in-vitro enzyme system for generation of CYP, AO and FMO derived metabolites of drugs, agrochemicals and other small molecules


    PolyCYPs+ metabolite kits are used by scientists in pharmaceutical and agrochemical companies to screen for and scale-up human and ot...
  • Product cGMP Protein and Antibody Purification

    KBI Biopharma has extensive experience developing purification processes for a wide variety of biotherapeutics, including: -Monoclonal antibodies-Bispecific antibodies -Enzymes -Fc fusion proteins -PEGylated proteins -Complex glycoproteins KBI supports 40+ annual programs ranging from FIH (First-in-Huma...
  • Product Aura Herbals Turmeric extract, curcumin drops (30 ml)

    Approximately 37 daily portions

    - the simplest composition, with no unnecessary additives
    - contains NovaSOL® turmeric extract
    - liquid curcumin solubilizate - high bioavailability of the extract

    NovaSOL® is a solubilization technology which increases the assimilabilit...
  • Product Cannabigerol (CBG)

    White to off white crystalline powder, free flowing and free from visible contamination



  • Product Core Technologies and Services

    • API / GMP Manufacturing • Rapid Process Development, Flawless Upscaling, and Economy of Scale-Production  • Simulated-Moving Bed (SMB) Chromatography  • Heterocyclic, Hazardous and Malodorous Chemistries • Organometallic and Cryogenic Chemistry • Transition-Metal Catalysis • High-Pressur...
  • Product C18 & C8 Phases for Peptide Purification

    We offer C18 and C8 spherical silica for peptide purification: • Available in metric tons • Effective regeneration protocols • Offered in bulk or packed in cartridges
    We also offer R&D Services: • Method development, optimization & transfer • Process scaling-up & transfer to producti...
  • Product Maxicaps® MR2 Virosart® HF

    High speed virus filtration. The high flux PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Maxicaps® MR Virosart® represents an integrity testable, sterile and fully single-use large scale virus filtration solut...
  • Product Pharma Separators

    GEA pharma separator skids aseptic and pure are energizing the industry with two comprehensive and sophisticated separator lines and one revolutionary new multi-bowl solution. These plug & produce pharma separator skids are breaking new ground in ensuring maximum safety, maximum yield and perfect adaptatio...
  • Product CANNON

    ALL IN ONE- CANNON IS THE FORMULA OF LIFEMEN & WOMEN

    Super nutrients, formulated in Denmark Ignite An Explosive Boost To Your: • Sexual Health   •  Mental Health  • Joints Health  • Aging and metabolism 
  • Product HEPES and HEPES Sodium Salt Buffers

    Our latest investment in new manufacturing capacity significantly expands our portfolio of in-house-produced biological buffers and moves Advancion into a leading global supply position for the HEPES molecule. HEPES Biologics Plus grade buffer products are produced by Advancion in its Sterlington facility ...
  • Product Biotage® Flash 150 Chromatography Systems

    Batch purification 80% faster than glass columns, 500g samples at 1L /min The Biotage® Flash 150 system supports batch purification up to 80% faster than traditional glass columns. Flash 150 is a simple, robust and reliable system, containing everything needed for large or industrial scale separations.
  • Product PIUR - TRANSIT

    Food supplement based on psyllium BIO and plant ingredient, a natural and gentle laxative that regulates transit and improves comfort.
    www.piur.fr
  • Product NUROM

    NUROM, is a combination of natural elements, based on Alpha-Lipoic acid, Carnosine, Zinc and Vitamin B with clinical trials showing efficacy in the prevention and treatment of (diabetic) neuropathy. NUROM can also be used in Peripheral Neuropathies: due to compression, trauma, inflammation, resulting i...
  • Product Komcyst -contains Gynaecological patented ingredient

    Komcyst is an innovative herb product extracted from fenugreek seeds and do not contain chemicals.

    It is natural and promising dietary supplement effective for management of Polycystic Ovary Syndrome (PCOS).

    Komcyst helps to:

    Ø  Increases insulin sensitizing activity &...
  • Product Contract manufacturing services for liquid herbal extracts

    Pilot, small-, and mid-scale manufacturing of liquid herbal extracts including fill-and-finish, labeling, and shipping to customer`s site. Manufacturing documentation and certificates can be included.

    Our integrated offering can include analytical testing, quality release, as well as product optimiz...
  • Product Multi Column Distillation Plant ( WFI Generation Plant)

    Multi Column Distillation plant ( Water for Injection Generation Plant) produces low conductivity pyrogen / endotoxin free Water For Injection (WFI) by stage distillation process. Our Plant is based on falling Film Evaporator Technology. • Capacity varies from 5 to 6,000 litres per hour • Desig...
  • Product PROFULL SENIOR SACHET

    Medical device for the treatment of overweight and obesity.
    MEDICAL DEVICE CE 0373 CLASS IIA
  • Product LC System & DAC Columns

    Whether it's capture and polishing of a biopharmaceutical, reverse phase chromatography of a microbial-derived protein, or ion exchange purification of an oligonucleotide, Asahi Kasei Bioprocess offers a range of chromatography equipment that is built for you.DAC HPLC Columns-Smaller molecular weight thera...
  • Product Ectoin | Ectoine | medEctoin

    medEctoin is the only "Made in Germany" and 100% natural ectoine in the market qualified for the use in Pharmaceuticals, Healthcare Products and Medical Devices. bitops medEctoin (INCI: Ectoin) is a clinically studied and proven, very tolerable substance with inflammation-reducing and membranze-stabilizing...
  • Product Hybrid Fractionating Column

    Customized Hybrid Fractionating Column systems combine the multi-plate efficiency of fractional columns with the gentle reboiling effect of Wiped-Film Evaporators. This proven Hybrid technology allows the purification of heat-sensitive materials similar in volatility, which could not otherwise be separated...
  • Product ReliSorbTM Chromatographic media product line

    Resindion s.r.l. offers a wide range of highly porous polymeric functionalized resins that, thanks to the better interaction between the matrix and a given solute, permits the development of almost every conceivable chromatographic process. Specific products are designed for Ion exchange chroma...
  • Product Cimidona® – Ze 450

    For the treatment menopausal complaints with symptoms such as hot flushes, insomnia, irritability, fatigue and depressive mood.
    - NO. 1 TREATMENT IN SWITZERLAND - HORMONE-FREE & NATURAL - SAFE AND WELL TOLERATED
    This is an authorised medicinal product. Max Zeller Söhne AG, 8590 Romanshorn
  • Product Cabot Norit Activated Carbon API Purification Sample Kit and sample kit ...

    The Cabot Norit Activated Carbon API Purification Sample Kit was developed to help process chemists remove impurities and develop a synthetic scheme to manufacture compounds for clinical trials. Purify more compounds in less time. Order your kit today at cabotcorp.com/pharmakit

    The Cabot Norit Activ...
  • Product Soft-Gel Solvent Dry Scrubber

    Soft-Gel Capsules when put in a dry room to get dried, the air passing through it carries the oil from the surface of the capsules while passing through the tray driers and enters the return air duct which eventually chokes the return air filters and desiccant bed. To avoid shutdowns and frequent cleaning,...
  • Product Walk in Cooling Cabinet.

    The Walk-In Cooling Cabinets / cold rooms are designed according to ICH guidelines, WHO, MCA and USFDA requirements to maintain uniform conditions. They are superior in airflow distribution, temperature control technology, cabinet construction and are manufactured as per cGMP regulations.
    Biggest Walk...
  • Product CARBOFIL

    Powdered activated carbons (PAC) play a critical role in a vast and diverse range of applications. Decolorization, deodorization or the removal of other trace impurities are
    amongst the most common applications where PAC are widely used in the pharmaceutical as well as in the food & beverage indus...
  • Product API & INTERMEDIATES

    The CDMO Division of KD Pharma excels in the production of drug intermediates and API drug substances. We offer our customers the full spectrum of drug services: • R&D development material for preclinical studies       • Pilot plant for phase I, II and III supplies • Large scale p...
  • Product Sanitary SIVTEK- Hygienic Screening

    Galaxy sivtek pvt. Ltd offers a wide range of products which includes sanitary sivtek separator. Application: it is designed to outperform conventional mechanical sifters used for screening/sieving application in pharmaceutical industry. It can give more than double the throughput as compared to convention...
  • Product Small Molecule and Synthetic Therapeutic Workflows

    Organic Workflow Systems.
    Organic chemists synthesizing new molecules follow a general workflow with Synthesis, Purification, Work-Up, and Evaporation steps. Biotage has developed tools for every step of the process to expand the range of options and in order to truly make it faster, simpler...
  • Product PIUR - POWER

    Food supplement for your daily natural booster based on guarana, ginseng and vitamin c increases physical and intellectual performance and fights effectively fatigue.
    www.piur.fr
  • Product Afragil

    Many women spend almost one third of their lives in menopause. An increase in oxidative stress (OS) levels is observed during the menopause. During this period of time there are many symptoms which have an impact on the women’s quality of life. Currently, there is gap in the treatment of climacteric an...
  • Product FEMAGINAL PLUS ovules

    FEMAGINAL PLUS ovules is a medical device Class IIa based on an improved formula of Boricacid, Hyaluronic acid, Polycarbophyl, Lactic acid, Tocopheryl acetate, Vitamin A, 18-Betaglycyrrhetinicacid and Tea tree oil, indicated in the treatment of vaginal dryness, irritations, burning and infections.
    Wom...
  • Product EcoChyll X7 Turnkey Solvent Recovery System

    Ecodyst® is the global leader and innovator of the new generation of rotary evaporators. Using a proprietary and innovative self-cooling technology, Ecodyst has evolved the rotovap to be more efficient, to have a smaller footprint, and to be less costly to operate as compared with traditional methods. Ecod...
  • Product Thymox®

    Expectorant (used in productive cough associated with cold, and bronchitis). Digestive. Spasmolytic, carminative. Antioxidant.Balsamic, antiseptic for the throat and the respiratory system. Flavouring agent. Topical use: skin protecting.
  • Product lutein

    Specification:1) Orange crystal or powder or oil liquid2) Easily soluble in ethanol and acetone. 3) Insoluble in water.

    Application:Can be used as a feed additive, pigment and pharmaceutical material. When used as an antioxidant it can prevent many diseases, including cancer.
  • Product NATURAL SCRUBBING SALT (COSMETIC GRADE) "DIATOMi"

    Caltron is the manufacturer of a specially designed product for cosmetic Industry under the brand name “Aqua-Sil”. This granular looking snow white natural salt is used as a scrubbing agent in face wash and body scrub. Unlike other types of scrubbing agent, our product “Aqua-Sil” gets easily suspended in t...
  • Product Stenovit

    Stenovit is available in vials with a dosing cap, easy to use and with an elevated bioavailability of the ingredients; it is recommended to take one vial per day. 

    The clinical efficacy of stenovit in protecting blood vessels and microcirculation from oxidative stress has been published in ...
  • Product PharsNutri Monomor Compounds

    Skuny developed high purity active ingredient  from grams to tons of production, in which DMF registration has three, two are registered CEP, five is preparing, DMF file has more than 30 domestic and foreign pharmaceutical companies to establish and expand the cooperation.
  • Product Redgine - Red Skin Ginger Extract

    RedGine is a Red Skin Ginger product’s Brand from Herbal Indonesia, which consists of various kinds of red skin ginger derivative products for various applications.

    We have 3 variants of product, which are:
    1. Redgine PE 701 Extract (Suitable for food & beverages)
    2. Redgine PE 003 ...
  • Product Finished Formulations

    We are a leading third-party manufacturer of health supplements and nutraceuticals in private labeling with more than 800 product portfolios, you can make any type of tailor-made products in capsules, or tablets. effervescent, sprays, syrups, drops, sachets, powder, and candies. We have our in-house label...
  • Product Primabene premium natural oils

    Cold pressed, organic (bio) or refined: Primabene® offers more than 120 different natural vegetable oils for health, nutrition and cosmetics. From almond to vermouth oil, diverse in smell, taste, appearance and composition – Primabene® Premium Natural Oils have one thing in common: They are all natural ...
  • Product CBD Oil

    • Cannabis extract in hemp oil. CBD 5%, 10%, 20%. • Cannabis extract in MCT oil. CBD 5%, 10%, 20%. THC-free - no detectable d9-THC, THCV, CBN (i.e.<0,005%).

  • Product Natural Paclitaxel

    Product Name:  Natural Paclitaxel
    CAS:  33069-62-4
    Type:  APIs
    Formula:  C47H51NO14
    Sourcing:   Taxus yunnanensis Cheng et L. K. Fu;   Taxus wallichiana var. mairei (Leme & H. Lv.) L. K. Fu & Nan Li
    ASSAY:  98-101%
    Expiration...
  • Product Cannabidivarine (CBDV)

    【CAS No.】24274-48-4
    【Molecular Formula】C19H26O2
    【Molecular weight】286.41
    【Character】White or light yellow crystal powder
    【Solubility】It is almost insoluble in water, but can dissolve in ethanol, methanol and other organic solution.
    【Specification】95%
    【Source】Extract from Indus...
  • Product Aura Herbals Oregadrop - Oregano Oil Drops (30 ml)

    Approximately 60 daily portions

    - 100% natural ingredients
    - product suitable for vegans
    - oregano oil standardised for 80% carvacrol
    - the simplest composition, with no artificial additives
    - based on olive oil

  • Product Citric Acid Coated Granules

    Available in 96% w/w & 98% w/w

    Moisture Protective Coating

    25 Kg Paper bag lined with double polythene bags.
  • Product Meat Substitute: Mushroom Base Meat 'MMB (Mushroom Meat Base)'

    • FEATURES: World's first mushroom-derived meat alternative.High protein content (as meat).Mushroom base for meat alternative, low cost compared to other meat substitutes • APPLICATION: Can be used as a base material for meat alternative of beef/pork/duck  substitue, and insect meat substitute
  • Product JADON GEL ICE & HOT

    Unique composition with highest concentration of comfrey extract (15%) in EU. Jadon GEL ICE (cosmeceutical) is an emulsion gel for stiff musclesand joints. Its original formula contains a high amount of comfrey extract (7,500 mg/15% in one bottle) as well asa high content of other active substances (natur...
  • Product Astaxanthin

    AstaReal® Astaxanthin from the microalgae, Haematococcus pluvialis, is a natural carotenoid that can be found in arctic marine environments. Astaxanthin is what gives the pink and red color to salmon, shrimp and lobster.
    The most abundant source of Astaxanthin in nature is Haematoco...