Hygienic Dispenser for Even Smaller Quantities
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Application example: Filling of smallest amounts with the pharmaceutical dispenser 4VPHD6 from ViscoTec.
The new pharmaceutical dispenser 4VPHD6 expands the GMP design VPHD dispenser series by the dosing technology specialist ViscoTec.
Developed for hygienic applications in the pharmaceutical industry, biotechnology or medical technology, the Hygienic Dispenser series now impresses in numerous applications. In order to meet the demands of the market for even smaller dosing quantities, ViscoTec expanded the series by an additional dispenser. It is now possible to fill very small quantities of 0.1 ml or to dose continuously from 0.2 ml per minute. Previously, the pharmaceutical product portfolio achieved dosing volumes of 0.5 ml to 20 ml in filling applications and 0.5 ml/min to 300 ml/min for continuous dosing.
Areas of application of the pharmaceutical dispenser 4VPHD6
The new 4-stage dispenser 4VPHD6, with an additional stage, enables
dosing at a back pressure of >20 bar. This may be necessary, for
example, when injecting into HPLC systems (high performance liquid
chromatography) or when continuously dosing an active ingredient into an
extruder. The filling of certain pharmaceuticals is challenging for the
dosing technology. These include cross-linked hyaluronic acid,
shear-sensitive intermediates such as protein-laden solutions, solid
containing, abrasive pastes and highly potent active ingredients.
ViscoTec offers the ideal solution for exactly these low to highly
viscous pharmaceutical products: The pharmaceutical dispensers of the
VPHD series in hygienic design meet the requirements of materials that
are difficult to dose and enable shear-sensitive filling, conveying and
dosing regardless of viscosity.
Filling in the dental industry
Common
products in the dental industry are flowable composite filling materials made
of plastic and glass. They are used for sealings, restorations or core
build-ups. The viscous pastes need to be filled with absolute precision. The
hygienic dispensers – and especially the new 4VPHD6 – impress in three ways: On
the one hand, the new product in the portfolio allows an exact dosage of 0.15
ml, for example. A constant thread break thanks to programmable suck-back,
guarantees an absolute repeatable accuracy of >99 %. In addition, dosing and
filling is carried out with high precision. There is no contamination of the
packaging or the dosing needle. This creates cost savings, as there is no
material waste. The third advantage derives from the technology itself: The
endless piston principle is ideally suited for abrasive materials, due to
absolute gentle material handling.
At a glance:
▪
Smallest
quantities are filled with high precision
▪
Perfectly
suitable for abrasive and difficult to handle dosing materials
▪
Clean
thread breakage thanks to suck-back effect for repeatable dosing results
Continuous dosing of highly potent active ingredients
Continuous
Dosing: Very small quantities are dosed almost pulsation-free in a continuous
process. The 4VPHD6 can also impress in this area. In contrast to piston pumps,
where continuous dosing is not possible; and peristaltic pumps, which do not
dose precisely enough. Precise dosing is essential, especially for highly
potent active ingredients. The active pharmaceutical ingredients are effective
even in lowest concentrations – i.e. in hormone preparations or drugs for
cancer. An identical amount of volume flow must be provided throughout. This is
the only way to maintain the desired quality in the final product. With the
additional 4VPHD6, flow rates of less than 0.2 ml/min - 500 ml/min
pulsation-free can be achieved – for highly precise and reliable dosing
results. The dosing accuracy of the pharmaceutical dispensers is +/-1 %, and this
precision is often even exceeded in real applications. This enables ViscoTec to
meet the high requirements of the individual applications.
At a glance:
▪
Highest
dosing accuracy
▪
Pulsation-free
▪
Absolute
repeatable accuracy
▪
Smallest quantities of low to high viscosity materials
ViscoTec endless piston principle
As
in the entire portfolio of the dosing technology specialist, the endless piston
principle is also included in the now expanded Hygienic Dispenser series. A
stainless steel rotor conveys the product by an eccentric movement in an
elastomer stator. The so-called endless piston principle is based on the
alternating opening of transport chambers whose volume does not change during
conveying from the suction to the discharge side. This means that the product
to be dosed is not compressed and is conveyed with very little shear. In the
cross-section of the rotor-stator geometry there is always a constant product
quantity, whereby a pulsation-free and highly precise conveying takes place. A
freely adjustable suck-back at the end of the dosing process prevents dripping
and, in the case of highly viscous products, a clean thread break is achieved.
You can find more
information about dosing and filling technology for the pharmaceutical industry by clicking below.
![ViscoTec Pumpen- u. Dosiertechnik GmbH](https://www.cphi-online.com/c267601th_S-comp267601.jpg)
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