Horizon & Promega Ink Predictive Disease Model Pact
The partnership aims to develop next-generation predictive human disease models as they occur in patient tumors.
UK translational genomics company Horizon Discovery Ltd. has established a partnership with Promega Corp. for the delivery of endogenous gene reporting capabilities with Promega’s luciferase and HaloTag reporter technologies, using Horizon’s homologous recombination-based precision genome editing technology (rAAV GENESIS).
The partnership aims to develop next-generation predictive human disease models as they occur in patient tumors. To date, Horizon has applied its rAAV gene-editing platform to reconstitute more than 370 cancer mutations and variations in human cell lines that serve as patient-relevant, predictive in vitro models of genetic disease.
Additional objectives will be to enable the study of tumor response to anti-cancer treatments in real-time, by offering
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