ETADEX SULFOBUTYL ETHER SODIUM

Betadex Sulfobutyl Ether Sodium is a kind of high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules. As a result,excllent performance can be available in many aspects. It helps enhance drug stability, solubility and safety, reduce drug toxicity and hemolysis, cover up smell, and control drug release.


Application


Solubilization: 

Neutral, positive, and negative drug substances can be effectively combined with sulfobutyl beta-cyclodextrin to increase the solubility of compounds in the drug solution by 10 to 25,000 times.

convenient for administration:

Sulfobutyl betacyclodextrin sodium has good biocompatibility and can be administered by injection, oral, ocular, nasal, topical and inhalation.

Good security:

It is usually eliminated from the kidneys quickly and completely after administration. In vitro and in vivo acute, subacute and chronic toxicity studies provide safe data and are approved for use in human pharmaceutical preparations.

Good stability:

The interaction with sodium sulfobutyl beta-cyclodextrin provides a beneficial protective environment for the drug substance in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility to provide solubility and stability.