Enalapril maleate tablets USP 5 mg, vasonrm – 5

Kopran Limited offers a wide range of products enalapril maleate tablets USP 5mg, vasonorm – 5. It belongs cardiovascular category. Antihypertensive enalapril, after hydrolysis to enalaprilat, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The beneficial effects of enalapril in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin- aldosterone system. Inhibition of ACE results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decrease aldosterone secretion. Although the latter decrease is small, it results in small increases of serum potassium. Packing: Box of 10 x 10's. Indications: Indicated for the treatment of: hypertension in patients for whom combination therapy is appropriate, used as an adjunct to the treatment of congestive heart failure.