Dual-Mix®, innovative error-free system for drug reconstitution
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Technoflex | Dual-Mix®
Dual-Mix® is a patented dual-chamber bag designed to hold a medicine in powder/lyophilizate form and its associated diluent. It enables the packaging of unstable molecules which need to be reconstituted just before administration to the patient. Dual-Mix®, has received the award for Excellence in Pharma in the Packaging category at the 2018 CPHI awards.
The bag is delivered sterile and consists of a lower chamber for the diluent and an upper chamber for the main active ingredient. The latter is the component which requires the highest protection. So, a peelable aluminium label, which can be placed on both sides of the bag, protects the powder or the lyophilisate from light and humidity. It is easy to detach at the time of use, and the nurse can very simply check the integrity of the product before its reconstitution.
The two chambers are separated by a peelable seal. It is sufficiently hard wearing not to break spontaneously during transport or storage, but is however easy to break by using simple appropriate pressure on the lower chamber to ensure that the main active ingredient and its diluent are mixed just before infusion. Reconstitution is achieved in under 10 seconds and in a totally safe way. The bag’s closed system ensures that the product is sterile and avoids risks of contamination during handling. Finally, Dual-Mix® has a twist-off compatible with the majority of trocars and infusion sets used in Europe and the United States. Dual-Mix® is available in three different volumes of 50, 100 and 250ml. and opens the way for standardised ready-to-use doses of medicines. By avoiding the need in some cases for preparation in the hospital pharmacy, Dual-Mix™ optimises preparation and administration by medical staff. A not inconsiderable advantage and a great advance, making reconstitution and administration simple, fast and totally safe in a hospital environment, but also during hospitalisation at home or in emergency or conflict zones.
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