DAUNORUBICIN HYDROCHLORIDE

Daunorubicin HCl


Cas No.: 23541-50-6


Chemical Name:

10-[(3-Amino-2,3,6-trideoxy-indole-L-lysylpyranyl)oxy]-7,8,9,10-tetrahydro-6,8,11- Hydrochloride of trihydroxy-8-acetyl-1-methoxy-5,12-naphthalenedione (8S-10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy -ɑ-L-lyxo-hexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride


Traits:

Orange-red crystalline powder; hygroscopic


Storage:

Shade, seal and store in a cool dry place.


use:

Cytotoxic drug


Clinical application:

1, acute granulocyte leukemia: whether it is a single use of daunorubicin or combined with other anti-tumor drugs, daunorubicin is suitable for the treatment of the various stages of the disease. Also used to treat promyelocytic leukemia.

2, acute lymphocytic leukemia: treatment of the disease with daunorubicin, the remission rate is very high, but due to its side effects and other effective treatments, daunorubicin is only suitable for those who have developed resistance to other drugs Case of medicine. The combination of daunorubicin, prednisone and vincristine in the acute phase of acute effusion has proven to be very successful.

3, other tumors: daunorubicin has been observed to have a good effect on neuroblastoma and rhabdomyosarcoma.