CROSCARMELLOSE SODIUM

CCS is an internally cross-linked

polymer of sodium carboxymethyl

cellulose and at Accent is available as

Acrocell. Possessing the nature of being

cross-linked, it is insoluble, hydrophilic

and highly absorbent. Being uniquely

fibrous, it holds remarkable water

wicking capabilities. CCS improves

bioavailability of formulations through

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its drug dissolution and disintegration

attributes. E468 cross-linked sodium

carboxymethyl cellulose acts as a food

emulsifier.

APPLICATION OF CCS

• Rapid disintegrator in

pharmaceutical formulations for

tablets, capsules and granules

• CCS effectively combines with

insoluble and filler binders such as

MCC and DCP

• It is preferable for non-starch base

formulation products

• CCS being a rapid disintegrator,

tablet dissolution can be easily

achieved

• Efficient for low use of levels

• CCS works well for insensate

hardness of tablets & finer

dissolution stability for a long term

• Used in solid-dosage forms,

vitamins and other nutrition