Cellicon® Perfusion Filter and Controller

Cationic lipid used in the preparation of liposomes and lipoplexes. Specifically, R-DOTMA chloride with its positive charge allows the protective loading of nucleic acids into lipid nanoparticles and promotes their endosomal release. Merck as the solely manufacturer of DOTMA-Cl can provide you with high-pu...

Based on our unique lipid processing and isolation techniques Merck’s helper lipid DOPE demonstrates outstanding solubility and thus distinctive physico-chemical properties in comparison to conventional amorphous DOPE’s. Those improved handling properties facilitate your LNP formulation process 

With 15+ years of contract development and manufacturing experience, Millipore® CTDMO Services offers leading expertise in the conjugation of drug linkers to monoclonal antibodies (mAbs). As ADC and Bioconjugation CDMO, we have comprehensive experience in conjugation technologies backed by broad analytical...

Choose API processing to improve API properties right from the start and avoid the risk of dealing with a poorly water-soluble API in formulation development or the need to start API development from scratch.

 

Whichever API processing method you decide to use, we pr...

Benzonase® endonuclease is a unique, genetically engineered endonuclease that offers a variety of advantages over existing methods of nucleic acid removal. This enzyme has been designed to be supplied without protease activity and without the viral contaminants that can accompany enzymes isolated from ...

Choosing the right partner for analytical and biosafety testing is critical in the race to approval. Our BioReliance® Contract Testing Services offer exceptional, risk-mitigating solutions with technical and regulatory expertise, to help bring life-changing drugs to market.

Increase Your Bioreactor Productivity with our superior solution for upstream process intensification. In combination with your bioreactor, the Cellicon® Cell Retention Solution allows you to achieve significantly higher viable cell densities, improving your upstream productivity and manufacturing flexibil...

ChetoSensar™ is our novel solubilization technology for hydrophobic ADCs.

Increased ADC solubility, important for reaching high DARWider therapeutic index and higher drug efficacyImproved bioconjugation efficiencyChetoSensar™ and ready-to-conjugate drug linkers available as samples or within ADC...

Deviron® C16 detergent provides robust inactivation of enveloped viruses. In addition, it may be used to achieve cell lysis for viral gene therapy vector production processes. It does not require a REACH authorization and is a suitable alternative to Triton™ X-100  detergent.

High-purity and high-quality DMG-PEG2000 enabling a consistent supply from development to commercial scales. 

A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments

Advanced intermediateEnables rapid synthesis of dolastatin-10 payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample.

In the Packaging Innovation Theatre from CPHI Milan this year, sponsored by the Alliance of the RTU, we held a panel on: ‘Elevating Brand Perception: Integrating Advocacy Projects into Business Strategies’. The session aimed to explore how pharmaceutical companies integrate advocacy projects into the core of their business, and how they can implement marketing strategies to address growing scrutiny and the demand for transparency along with social responsibility. 

Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters