ADC & Bioconjugation CDMO services

With Millipore® CTDMO Services we support small molecule API synthesis projects from milligram to commercial quantities. We are the partner to address the most difficult challenges, whether the target is difficult to handle, synthesize, or source. With a true consultative and partnered approach, our servic...

An innovative single-use film offering strength and leak resistance for your toughest liquid bioprocessing applications. Ultimus® film provides enhanced bag strength, improved durability and leak resistance through a novel strength layer reinforced by woven nylon. The inert fluid contact layer promotes hea...

Millipore® CTDMO Services delivers expertise and flexible solutions for viral vector development and manufacturing to advance cell and gene therapies from preclinical through commercial production.

Our proficiency with adeno-associated virus (AAV), lentivirus, adenovirus, and other vectors helps...

The Viscosity Reduction Platform of proprietary excipient combinations enables subcutaneous formulation of highly concentrated protein biologics, bringing together increased concentrations and improved downstream processing.

Cationic lipid used in the preparation of liposomes and lipoplexes. Specifically, R-DOTMA chloride with its positive charge allows the protective loading of nucleic acids into lipid nanoparticles and promotes their endosomal release. Merck as the solely manufacturer of DOTMA-Cl can provide you with high-pu...

Based on our unique lipid processing and isolation techniques Merck’s helper lipid DOPE demonstrates outstanding solubility and thus distinctive physico-chemical properties in comparison to conventional amorphous DOPE’s. Those improved handling properties facilitate your LNP formulation process 

Choose API processing to improve API properties right from the start and avoid the risk of dealing with a poorly water-soluble API in formulation development or the need to start API development from scratch.

 

Whichever API processing method you decide to use, we pr...

Benzonase® endonuclease is a unique, genetically engineered endonuclease that offers a variety of advantages over existing methods of nucleic acid removal. This enzyme has been designed to be supplied without protease activity and without the viral contaminants that can accompany enzymes isolated from ...

Choosing the right partner for analytical and biosafety testing is critical in the race to approval. Our BioReliance® Contract Testing Services offer exceptional, risk-mitigating solutions with technical and regulatory expertise, to help bring life-changing drugs to market.

A Superior Cell Retention Solution for N-1 Seed Train Intensification with Optimized Process Control. The benchtop Cellicon™ Perfusion Solution is designed to meet your perfused seed train challenges. It consists of a controller and a flat sheet cell retention filter with a single-use assembly running in t...

Increase Your Bioreactor Productivity with our superior solution for upstream process intensification. In combination with your bioreactor, the Cellicon® Cell Retention Solution allows you to achieve significantly higher viable cell densities, improving your upstream productivity and manufacturing flexibil...

ChetoSensar™ is our novel solubilization technology for hydrophobic ADCs.

Increased ADC solubility, important for reaching high DARWider therapeutic index and higher drug efficacyImproved bioconjugation efficiencyChetoSensar™ and ready-to-conjugate drug linkers available as samples or within ADC...

In the Packaging Innovation Theatre from CPHI Milan this year, sponsored by the Alliance of the RTU, we held a panel on: ‘Elevating Brand Perception: Integrating Advocacy Projects into Business Strategies’. The session aimed to explore how pharmaceutical companies integrate advocacy projects into the core of their business, and how they can implement marketing strategies to address growing scrutiny and the demand for transparency along with social responsibility. 

Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters