BMS and Gilead Sciences Sign Licensing Agreement
The companies have signed a licensing agreement for the development and commercialization of the REYATAZ and cobicistat fixed-dose combination.
New York-based drug maker Bristol-Myers Squibb and California-based biopharmaceutical company Gilead Sciences, Inc. announced Wednesday a licensing agreement for Bristol-Myers Squibb to develop and commercialize a fixed-dose combination containing Bristol-Myers Squibb's protease inhibitor REYATAZ? (atazanavir sulfate) and Gilead's cobicistat, a pharmacoenhancing or "boosting" agent that increases blood levels of certain HIV medicines to potentially allow for one pill once daily dosing.
REYATAZ is a prescription medicine used in combination with other medicines to treat people 6 years of age and older who are infected with the human immunodeficiency virus (HIV).
Cobicistat is Gilead's proprietary potent mechanism-based inhibitor of cytochrome P450 3A (CYP3A), an enzyme that metabolizes drugs in
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