Food Studies Brochure
Alcami is equipped and ready to handle study design and execution of food studies to support a variety of oral solid dosage forms, including tablets, capsules, and suspensions. Our subject matter experts have developed and executed studies using infant formula, yogurt, orange juice, apple sauce, smoothies, and a variety of other foods and drinks.
Alcami
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US
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2016On CPHI since
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1000 - 4999Employees
Other Content from Alcami (2)
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News Alcami to manufacture PharmaTher’s proprietary ketamine products
The CDMO will supply expertise in GMP sterile fill-finish manufacturing and controlled-substances -
Webinar Expanding the OSD Toolbox with an Industry-Based Approach to Lipid and Surfactant Adsorption onto Dry Powder Excipients to Increase the Dissolution Rate of BCS Class II and Class IV Active Pharmaceutical Ingredients (API’s)
Common high-performance lipids and surfactants were used to improve the dissolution rate of furosemide as a model compound for BCS Class II and Class IV active pharmaceutical ingredients. Furosemide equilibrium solubility was measured throughout an HLB range (1-16) of liquid lipids and surfactants. Furosemide tablets were then manufactured using high shear granulation to absorb the solubilized and suspended furosemide onto microcrystalline cellulose (Avicel PH101). The granulations were then compressed using a rotary tablet press and standard tablet tooling. Finished tablets were analyzed to compare dissolution rates using 0.1 N HCl media and USP Apparatus II. Higher equilibrium solubility yielded increased dissolution rates for furosemide tablets compared to directly compressed furosemide tablets.
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