9
Apr
2025

ICE S.p.A

Exhibitor at CPHI Japan 2025 stand 5R-21
About Us

ICE Pharma is a niche API and speciality ingredients company focused on the development and manufacture of bile acid derivatives. ICE is one of the world’s main producers of Ursodeoxycholic Acid (UDCA). ICE Pharma has an integrated global manufacturing network in Europe, Latin America, Asia and Oceania that serves customers in over 50 countries. ICE Pharma’s five R&D centres have enabled it to develop a unique and comprehensive range of bile acid products including generic APIs, excipients, and new chemical entities. 

  • IT
  • 2015
    On CPHI since
  • 4
    Certificates
  • 1000 - 4999
    Employees
Company types
Manufacturer/Innovator
Primary activities
Pharmaceutical Company (generic finished products)
Pharmaceutical Company (innovator finished products)
Contact info
Event information
CPHI Japan 2025
  • 09 Apr 2025 – 11 Apr 2025
  • East Halls 4, 5 & 6, Tokyo Big Sight, Tokyo, Japan
  • Visit us at stand 5R-21

Products Featured at CPHI Japan 2025

  • Chenodeoxycholic Acid or Chenodiol

    Product Chenodeoxycholic Acid or Chenodiol

    ICE S.p.A provides a wide range of products which includes chenodeoxycholic acid or chenodiol. It is a natural substance found in human bile. it's used in the treatment of gall stones disease and it's obtained by synthesis starting from cholic acid. it's used as intermediate for ursodeoxycholic acid manufa...
  • Chenodeoxycholic Acid Sodium Salt

    Product Chenodeoxycholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes chenodeoxycholic acid sodium salt. It has been the same pharmacological properties of chenodeoxycholic acid. It reduces cholesterol amount, probably by inhibiting liver synthesis, allowing gallstones dissolution. Packaging: lab or pilot scale scale...
  • Cholic Acid Pharmaceutical Grade

    Product Cholic Acid Pharmaceutical Grade

    ICE S.p.A provides a wide range of products which includes cholic acid pharmaceutical grade. It has been detected in the bile of most vertebrates in conjugation with glycine and taurine. It's one of the end product of cholesterol metabolism. Packaging: 25, 50 Kg in fiber drum with a double PE inner bags. s...
  • Dehydrocholic Acid

    Product Dehydrocholic Acid

    ICE S.p.A provides a wide range of products which includes dehydrocholic acid. It is a bile acid obtained by oxidation of hydroxyl groups in position 3, 7 and 12. and it's used to increase the volume and the water content of the bile to improve biliary drainage. Packaging: 25, 50 Kg in fiber drum with a do...
  • Deoxycholic Acid

    Product Deoxycholic Acid

    ICE S.p.A provides a wide range of products which includes deoxycholic acid. It is a natural substance found in the intestine as secondary biliary obtained by an enzymatic process from cholic acid. It's mainly used in the preparation of steroids. It's extracted from bovine bile where is found conjugated wi...
  • Glicocholic Acid Sodium Salt

    Product Glicocholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes glicocholic acid sodium salt. It's used as a detergent and in the preparation of microbiological media. It's used as a water soluble form of glycocholic acid. Packaging: lab or pilot scale product. Storage: store in a tightly closed container in a ...
  • Glicodeoxycholic Acid Sodium Salt

    Product Glicodeoxycholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes glicodeoxycholic acid sodium salt. It's commonly used as detergent. Packaging: lab or pilot scale scale product. Storage: store in a tightly closed container in a cool and dry place.
  • Glycocholic Acid

    Product Glycocholic Acid

    ICE S.p.A provides a wide range of products which includes glycocholic acid. It's the main component of human bile and it's obtained by synthesis starting from cholic acid. Mainly used as biological enhancer, solubility agent and drug carrier. It's listed as a GRAS ( generally recognized as safe) substance...
  • Glycoursodeoxycholic Acid

    Product Glycoursodeoxycholic Acid

    ICE S.p.A provides a wide range of products which includes glycoursodeoxycholic acid. It's the product of the conjugation between ursodeoxycholic acid and glycine. It ‘s a secondary bile acids obtained by enzymatic process by intestine microbial flora. Packaging: lab or pilot scale product. Storage: store ...
  • Lithocholic Acid

    Product Lithocholic Acid

    ICE S.p.A provides a wide range of products which includes lithocholic acid. It's a bile acid that acts as a detergent to dissolve fats and improve their absorption. It's under study as a biomarker of intra-hepatic cholestasis of pregnancy during ursodeoxycholic acid treatment. Packaging: 25, 50 Kg in fibe...
  • Natural Taurine

    Product Natural Taurine

    ICE S.p.A provides a wide range of products which includes natural taurine. It is a natural amino acid widely found free and conjugated in animals tissue but pratically absent in vegetal world. It's extracted from mother liquor of bovine bile hydrolysis and it's used as additive in milk for babies, health ...
  • Sodium Cholate

    Product Sodium Cholate

    ICE S.p.A provides a wide range of products which includes sodium cholate. It's obtained from cholic acid. It has been used to prevent gallstones generation and generally as drug carrier. It has been used in the preparation and formulation of microbiological media. Packaging: 25, 50 Kg in fiber drum with a...
  • Sodium Deoxycholate

    Product Sodium Deoxycholate

    ICE S.p.A provides a wide range of products which includes sodium deoxycholate. It's obtained from deoxycholic acid. It's used as an anionic detergent in the extraction of the membrane receptors and to isolate proteic ions. It's also used in the preparation of microbiological media. Packaging: 25, 50 Kg in...
  • Taurocholic Acid Sodium Salt

    Product Taurocholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes taurocholic acid sodium salt. It's the sodium salt form of the conjugation between Taurine and Cholic acid and it's naturally found in almost all mammal animals. It's used as a biological enhancer, solubilization agent and drug carrier. Packaging: ...
  • Taurodeoxycholic Acid Sodium Salt

    Product Taurodeoxycholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes taurodeoxycholic acid sodium salt. It's the sodium salt form of the conjugation between taurine and deoxyholic acid. It's a biological and very efficacious detergent. It's used as a vehicle to support drug or vaccines delivery. Packaging: 25, 50 Kg...
  • Tauroursodeoxycholic Acid

    Product Tauroursodeoxycholic Acid

    ICE S.p.A provides a wide range of products which includes tauroursodeoxycholic acid. It is obtained conjugating ursodeoxycholic acid and taurine. It's used for dissolving cholesterol radio lucent gallstones, for treating chronic liver diseases with cholestasis, for treating primary biliary cirrhosis and v...
  • Tauroursodeoxycholic Acid Sodium Salt

    Product Tauroursodeoxycholic Acid Sodium Salt

    ICE S.p.A provides a wide range of products which includes tauroursodeoxycholic acid sodium salt. It has detergent property. Literature reports about its action in inhibiting human cholangiocarcinoma growth. Packaging: lab or pilot scale scale product. Storage: store in a tightly closed container in a cool...
  • Ursodeoxycholic Acid or Ursodiol

    Product Ursodeoxycholic Acid or Ursodiol

    ICE S.p.A provides a wide range of products which includes ursodeoxycholic acid or ursodiol. It is a hydrophilic bile acid that occurs naturally in bile. It's obtained by synthesis starting from cholic acid. It is used to produce level of cholesterol in the bile and for dissolution of cholesterol, radio-lu...