Tamoxifen

Tamoxifen
Product Description

Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.

CLEARSYNTH LABS LIMITED

  • IN
  • 2015
    On CPHI since
  • 2
    Certificates
  • 250 - 499
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
Agrochemical
Analytical Services
Biopharmaceutical
Clinical Research
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Intermediates Manufacturer
Pharmacy
Specifications
  • CAS Registry Number
    10540-29-1

CLEARSYNTH LABS LIMITED

  • IN
  • 2015
    On CPHI since
  • 2
    Certificates
  • 250 - 499
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
Agrochemical
Analytical Services
Biopharmaceutical
Clinical Research
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Intermediates Manufacturer
Pharmacy

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