Synta to Launch Lung Cancer Drug Trial
Synta Pharmaceuticals is set to initiate a Phase 2b/3 clinical trial of ganetespib in combination with docetaxel in non-small cell lung cancer in the second quarter of 2011.
Synta Pharmaceuticals has announced that it will initiate a Phase IIb/III clinical trial of ganetespib (STA-9090) combined with docetaxel in non-small cell lung cancer in the second quarter of 2011.
The trial will evaluate treatment with ganetespib plus docetaxel versus docetaxel alone, with 1:1 randomisation, in patients with Stage IIIB or IV non-small cell lung cancer who have completed one prior systemic therapy for advanced disease.
The first, Phase IIb portion will evaluate efficacy as measured by progression-free survival in approximately 240 patients. Results from this stage will be used to inform the choice of patient sub-population for the second, Phase III portion.
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