Scancell Develops New Vaccine against Lung Cancer
The vaccine, known as SCIB2, stimulates immune responses to the lung cancer antigen NY-ESO-1 and may also have potential utility in oesophageal, liver, gastric, prostate, ovarian and bladder cancers.
Scancell Holdings Plc, the developer of therapeutic cancer vaccines, has announced that a treatment utilising a DNA vaccine based on its ImmunoBody technology, in combination with Homspera, an adjuvant developed by ImmuneRegen BioSciences, Inc. has produced encouraging anti-tumour results in animal models.
The vaccine, known as SCIB2, stimulates immune responses to the lung cancer antigen NY-ESO-1 and may also have potential utility in oesophageal, liver, gastric, prostate, ovarian and bladder cancers. Unlike classical adjuvants, Homspera did not enhance the SCIB2 systemic immune response but did make it more effective at the tumour site. This could have profound implications for cancer vaccine therapy.
Scancell is currently conducting a Phase I clinical trial utilising its SCIB1
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