Insulin glargine.
Dosage form: solution for subcutaneous injections in 3 ml cartridges and pre-filled disposable insulin pen.
·
Long-acting
basal insulin
·
Maintains
normal physiologic concentration of basal (background) insulin
·
Most
widely used basal insulin analogue. Is the reference product for all basal
insulins.
· Increased
duration of action of insulin glargine is associated with subcutaneous microprecipitate
generation from which small amounts of insulin glargine permanently release,
which makes it possible to administer the product once a day.
·
Concentration:
U100
·
Onset
of action after subcutaneous administration – in 1 hour
·
29
hours – maximum action
·
24
hours – duration of action