Protein stabilizer portfolio

Poor solubility of APIs is a critical challenge in the drug development process. Our Parteck® MXP range of polymers includes two polyvinyl alcohol-based excipients, specifically designed and optimized for hot melt extrusion to increase solubility for a broad range of APIs.

 
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Parteck® PLX 188 is a dissolution rate enhancing excipient that also acts as a robust water-soluble, hydrophilic lubricant. With its optimized particle size, Parteck® PLX 188 poloxamer is designed with the needs of modern manufacturing in mind - such as direct compression and continuous manufacturing -...

Parteck® SLC mesoporous silica is a multi-functional excipient for both solubility enhancement and particle engineering.

When used as a solubility enhancing excipient, the high surface area and small pores of Parteck® SLC mesoporous silica enable optimal stabilization of the more solubl...

Advanced intermediate.Enables rapid synthesis of PBD payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample

Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance. Ideal for single-use tangential flow filtration (TFF), Pellicon® Capsules provide high flux and linear scalability in a plug ‘n play format for optimum process flexibility and productivity. Pelli...

An Easy-to-Use GMP Process Analytical Technology (PAT) Platform to Monitor Cell Cultures In-Line and in Real-Time, from Process Development to Manufacturing

With Millipore® CTDMO Services we support small molecule API synthesis projects from milligram to commercial quantities. We are the partner to address the most difficult challenges, whether the target is difficult to handle, synthesize, or source. With a true consultative and partnered approach, our servic...

An innovative single-use film offering strength and leak resistance for your toughest liquid bioprocessing applications. Ultimus® film provides enhanced bag strength, improved durability and leak resistance through a novel strength layer reinforced by woven nylon. The inert fluid contact layer promotes hea...

Millipore® CTDMO Services delivers expertise and flexible solutions for viral vector development and manufacturing to advance cell and gene therapies from preclinical through commercial production.

Our proficiency with adeno-associated virus (AAV), lentivirus, adenovirus, and other vectors helps...

The Viscosity Reduction Platform of proprietary excipient combinations enables subcutaneous formulation of highly concentrated protein biologics, bringing together increased concentrations and improved downstream processing.

Cationic lipid used in the preparation of liposomes and lipoplexes. Specifically, R-DOTMA chloride with its positive charge allows the protective loading of nucleic acids into lipid nanoparticles and promotes their endosomal release. Merck as the solely manufacturer of DOTMA-Cl can provide you with high-pu...

Based on our unique lipid processing and isolation techniques Merck’s helper lipid DOPE demonstrates outstanding solubility and thus distinctive physico-chemical properties in comparison to conventional amorphous DOPE’s. Those improved handling properties facilitate your LNP formulation process 

In the Packaging Innovation Theatre from CPHI Milan this year, sponsored by the Alliance of the RTU, we held a panel on: ‘Elevating Brand Perception: Integrating Advocacy Projects into Business Strategies’. The session aimed to explore how pharmaceutical companies integrate advocacy projects into the core of their business, and how they can implement marketing strategies to address growing scrutiny and the demand for transparency along with social responsibility. 

Millistak+® HC Pro (high-capacity synthetic media) is a family of synthetic depth filters