Protein Production

Protein Production
Product Description

Custom Protein Services

We manufacture a wide variety of custom proteins including enzymes, growth factors, and nucleases. Aldevron can support custom protein manufacturing from Research through GMP quality grade. As part of that focus, we are also committed to the production of enzymes that synthesize and cap mRNA.




Gene Editing

We offer research-grade nucleases manufactured at our ISO 13485 facility, which includes SpCas9, SpyFi™, SaCas9, Cas12a and novel enzymes. We also supply GMP SpCas9 and SpyFi Cas9 as off-the-shelf products.




IVT Enzymes

We offer research-grade IVT enzymes manufactured at our ISO 13485 facility, which include Guanylyltransferase, 2'-O-Methyltransferase, T7 RNA Polymerase , Inorganic Pyrophosphatase, Poly(A) Polymerase, DNase I, and Ribonuclease Inhibitor.

Aldevron

  • US
  • 2022
    On CPHI since
  • 2
    Certificates
  • 1000 - 4999
    Employees
Company types
CMO/CDMO
Primary activities
Custom Manufacturing/Custom Synthesis

Aldevron

  • US
  • 2022
    On CPHI since
  • 2
    Certificates
  • 1000 - 4999
    Employees
Company types
CMO/CDMO
Primary activities
Custom Manufacturing/Custom Synthesis

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    Product CRISPR Nucleases

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    Aldevron manufactures CRISPR nucleases, including SpyFi™ Cas9 Nuclease, SpCas9, SaCas9, Cas12a, and associated variants. The table below shows Aldevron's CRISPR nucleases that are available in two quality grades, from research-grade through cGMP.


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  • IVT Enzymes

    Product IVT Enzymes

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    Our in vitro transcription (IVT) enzymes are qualified both by activity assays and functionally for RNA synthesis and can be custom manufactured to meet your specific project requirements from milligram to multigram scale
  • mRNA Manufacturing

    Product mRNA Manufacturing

    Aldevron produces high-quality mRNA to your specifications using scalable processes capable of delivering milligram to multi-gram quantities. Aldevron can also provide high-quality enzymes and linearized plasmid DNA for your in-house mRNA synthesis requirements.


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  • Nanoplasmidᵀᴹ

    Product Nanoplasmidᵀᴹ

    Looking to enhance performance and manufacturing from your DNA backbone, without the regulatory concerns? The small Nanoplasmid backbone fulfills all the requirements. The Nanoplasmid Vector System (<500 bp backbone) provides advantages over existing legacy plasmid DNA backbones and minicircles:
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  • Plasmid DNA Production

    Product Plasmid DNA Production

    Plasmid DNA for research, preclinical, and clinical applications scaled to fit projects of any size
    Aldevron has been perfecting plasmid DNA production for more than 20 years, using proprietary technology to manufacture DNA for a wide range of research, preclinical, clinical, and diagnostic applicatio...

Aldevron resources (1)

  • Brochure mRNA-Synthesis with Multi-scale Production

    Aldevron makes mRNA for the most demanding applications. We build trust and confidence through open communication and focused teams that are committedto reaching your end goals. With mRNA manufactured by Aldevron, advance with confidence into and beyond your clinical stages of development. Aldevron mRNA services support these types of projects and we can also customize to your needs.
    • Protein Replacement Therapy
    • Cancer Immunotherapy
    • Genetic Reprogramming
    • Infectious Disease Vaccines
    • Genome Engineering
    • Allergy Vaccines
    • Gene Editing
    • Regenerative Therapies