Primojel®

Primojel®
Product Description

Primojel® sodium starch glycolate is a superdisintegrant suitable for various tablet and capsule formulations. In higher concentrations, Primojel® can act as a dissolution enhancing agent. Primojel® is highly effective when used intragranular and/or extragranular in dry/wet granulation processes.


Primojel® takes up more than 20 times its own weight of water. Rapid water penetration into the tablets and powerful swelling results in rapid disintegration. Studies show that Primojel® takes up more water than comparative products on the market and develops a strong disintegrating force making it a highly effective product.The botanical source, degree of cross-linking and degree of substitution of Primojel® have been optimized in order to enable rapid water uptake by the polymer without the formation of a viscous gel that may impede water penetration into the tablet.


Maintaining the native spheroid structure of potato starch grains supports the optimal flow properties of Primojel®

Read more Show less

DFE Pharma

  • DE
  • 2015
    On CPHI since
  • 1
    Certificates
  • 250 - 499
    Employees
Company types
Manufacturer/Innovator
Other
View company profile
Categories
more categories Show less
Specifications
  • Supplied from
    Netherlands
More specifications Fewer specifications
Sales Markets
Show more Show less

DFE Pharma

  • DE
  • 2015
    On CPHI since
  • 1
    Certificates
  • 250 - 499
    Employees
Company types
Manufacturer/Innovator
Other
View company profile

More Products from DFE Pharma (13)

  • SuperTab® 40LL

    Product SuperTab® 40LL

    SuperTab® 40LL is a co-processed excipient combining anhydrous lactose with lactitol. SuperTab® 40LL combines all required functionalities into one single excipient. It redefines the limits of direct compression, making it the excipient of choice for mini-tablet and/or other challenging formulations. qq...
  • BioHale® Sucrose

    Product BioHale® Sucrose

    BioHale® Sucrose is a non-reducing crystalline disaccharide made up of glucose and fructose. Sucrose is commonly used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates during the formulation process. The utility and function is driven by its unique chemical and physical pro...
  • BioHale® Trehalose Dihydrate

    Product BioHale® Trehalose Dihydrate

    BioHale® Trehalose Dihydrate is a non-reducing disaccharide consisting of two glucose molecules which are linked by an α, α-1,1 bond. It is used in the pharmaceutical industry as a stabilizer of biologics.

    Trehalose Dihydrate has proven to be highly effective in protecting cell membranes...
  • Lactohale® 200

    Product Lactohale® 200

    Lactohale® 200 is milled lactose produced with a tightly controlled mean particle size. The size of the particles of Lactohale® 200 can be controlled and but also varied by gentle milling. This means that different D50's can be produced depending on the degree of milling to match the cust...
  • Lactohale® 300

    Product Lactohale® 300

    Lactohale® 300 is a very fine and micronised lactose with a D50 below 5 microns. Lactohale® 300 is applied to Dry Powder Inhalation formulation to improve the drug deposition or optimize the flow properties of their formulation. In addition, Lactohale® 300 can be blended with several coarse lactose gra...
  • Respitose® SV014

    Product Respitose® SV014

    Respitose® SV014 is a sieved inhalation-grade lactose grade with excellent flow properties and very large lactose crystals. It’s optimal flow properties provides opportunities for application in reservoir devices or to maintain the required flow and content uniformity in high dose inhalation formulatio...
  • Pharmatose® 100M

    Product Pharmatose® 100M

    Pharmatose® 100M is a highly consistent monohydrate lactose. It’s a pure white, crystalline lactose that is sieved to varying particle sizes, allowing pharmaceutical companies to choose the grade that best fits their formulation needs. This type of lactose is typically used for sachets and capsul...
  • Primellose®

    Product Primellose®

    Primellose® is DFE Pharma’s product brand name for croscarmellose sodium and It is suitable for various tablet and capsule formulations. Primellose® is effective in combination with both insoluble and soluble filler-binders at concentrations of 2%w/w - 6%w/w. Primellose® is effecti...
  • Pharmacel® 112

    Product Pharmacel® 112

    Pharmacel® 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. 1.5% w/w), especially designed for formulating active pharmaceutical ingredients (APIs) with a high sensitivity for moisture.

    Pharmacel® 112 can be used in a wide range of oral ...
  • Pharmatose® 200M

    Product Pharmatose® 200M

    DFE Pharma offers a wide range of milled and sieved lactose products, including the Pharmatose® and Lactochem® brands. Varying degrees of particle sizes can be offered to allow pharmaceutical companies to choose the grade best fitting their formulation needs. Milled lactose compacts well due t...
  • SuperTab® 11SD

    Product SuperTab® 11SD

    SuperTab® 11SD is a highly consistent, spray-dried monohydrate lactose enabling efficient tableting by offering free flow properties. It is designed to combine the high compactibility of finely milled lactose with good flow properties of spherical spray-dried particles. For those formulators that requi...
  • SuperTab® 21AN

    Product SuperTab® 21AN

    SuperTab® 21AN is a highly consistent anhydrous lactose with excellent compaction and re-compaction. Its low moisture content makes SuperTab® 21AN a popular choice in formulating with moisture sensitive API’s. For those formulators that require additional compaction and/or flow DFE Pharma offers SuperT...
show all 13 other products

DFE Pharma resources (6)

  • Excipients – an industry adapting to change

    News Excipients – an industry adapting to change

    Excipients are a crucial component of the pharmaceutical product formulation, and the industry is constantly having to adapt to changes in demand and technology innovations
    15 Mar 2021
  • Nitrosamines Risk Mitigation

    Whitepaper Nitrosamines Risk Mitigation

    Assessing nitrosamines in drug products has become one of the top challenges for formulators in the pharmaceutical industry.

    During drug product risk evaluation, excipients play a crucial role. Although the risk of nitrosamine presence is low, some excipients contain trace amounts of nitrites. Under specific conditions, these traces can lead to nitrosamine formation within the drug product.

    Different studies reveal varying nitrite levels among different excipients and even within the same type from different suppliers. Comparing excipient types and suppliers is essential for risk mitigation during production.

  • Closer to the Formulator (C2F) Center

    Video Closer to the Formulator (C2F) Center

    The new Center of Excellence “Closer to the Formulator” (C2F) by DFE Pharma helps pharmaceutical companies to shorten the time from a concept to a finished commercial product through expertise in all phases of pharmaceutical development. 

    The services offered by this new state-of-the-art facility, are mainly focused on Oral Solid Dosage (OSD) forms, comprising all types of pre-registration work including development, intermediate scale-up, and technology transfer. 


     The C2F offerings can provide pharmaceutical companies with multiple advantages as, for example, it aims to significantly lower the number of development cycles and aspires to reduce formulation costs, when launching a medicine. 



    2024-06-20
  • Understanding and Accounting for Excipient Variability in Continuous Tablet Manufacturing (CM)

    Whitepaper Understanding and Accounting for Excipient Variability in Continuous Tablet Manufacturing (CM)

    As pharmaceutical production moves from batch-wise to continuous manufacturing, individual processing steps, such as blending of the active pharmaceutical ingredient (API) with excipients, have to be re-designed to continuous operations.

    Whilst the cost and quality benefits of CM are well documented, successful implementation relies on an in-depth understanding of how raw materials and their mixtures – including excipients – behave in continuous processes. This whitepaper will outline some of the key learnings from DFE Pharma’s excipients in CM processes variability experiments, before setting out DFE Pharma’s Stretch Batch Approach and how it can work in practice.
    Ultimately, it will demonstrate why DFE Pharma is fast becoming the pharma industry’s preferred global partner in the robust development of continuous tablet manufacturing processes.
  • DFE Pharma Norten Hardenberg, Germany

    Video DFE Pharma Norten Hardenberg, Germany

    DFE Pharma's Norten Hardenberg plant, located in Germany, is dedicated to the production of anhydrous lactose. An investment for the future, featuring a new state-of-the-art production line, like for like process, high-end control to ensure batch homogeneity.
    2021-10-11
  • We Are DFE Pharma

    Video We Are DFE Pharma

    DFE Pharma is a global leader in excipient products and services for usage in the pharmaceutical, biopharmaceutical, and nutraceutical industries. We strive to develop, produce and supply the highest quality functional excipients for oral solid dose, inhalation, and parenteral formulations. Our products play essential roles as fillers, binders, disintegrants, and stabilizing agents in formulations. 

    They enable the active ingredients to be dosed and released into the patients' system in a predictable, accurate, and effective manner. With over a century of experience, we are driven by our purpose your medicines, our solutions. Moving to a healthier world. #pharma #DFEPharma #excipients
    2021-09-24