Presage Biosciences extends research collaboration with Takeda to discover novel cancer drug combinations
The agreement provides Takeda access to Presage’s proprietary CIVO technology platform to enable identification of novel oncology drug combinations in solid tumours.
Presage Biosciences has entered into a multi-year extension of its November 2014 research alliance with Takeda Pharmaceuticals Company.
The agreement provides Takeda access to Presage’s proprietary CIVO technology platform to enable identification of novel oncology drug combinations in solid tumours. Under the agreement, Presage and Takeda will screen a broad array of drug combinations and preclinical models to discover novel combinations and generate data to support clinical decision-making on Takeda’s pipeline agents. The agreement includes development and regulatory milestones related to identification of successful novel drug combinations.
“We are pleased to extend our collaboration with Presage and utilize their technology platform to more rapidly understand the impact of drug combinations directly on tumours,” said Christopher Claiborne, Head of the Oncology Drug Discovery Unit at Takeda. “Takeda prides itself on creating novel medicines for patients, and having a committed partner like Presage enables us to continue fulfilling our mission of aspiring to cure cancer.”
“It is deeply rewarding to continue our collaboration with Takeda,” said Richard Klinghoffer, Chief Scientific Officer of Presage. “Together, the teams at Presage and Takeda are employing the unique potential of Presage’s CIVO arrayed micro-injection technology to identify novel drug combinations that will hopefully improve the lives of patients with cancer.”
CIVO technology is currently being used preclinically to identify effective combinations of drugs. By assessing several combinations in a single living tumour, the CIVO™ platform is able to characterize and directly compare the influence of multiple biophysical factors such as immune infiltrate, stromal barrier and hypoxia on the tumour response.
Related News
-
News CPHI Podcast Series: The power of proteins in antibody drug development
In the latest episode of the CPHI Podcast Series, Lucy Chard is joined by Thomas Cornell from Abzena to discuss protein engineering for drug design and development. -
News Amgen sues Samsung biologics unit over biosimilar for bone disease
Samsung Bioepis, the biologics unit of Samsung, has been issued a lawsuit brought forth by Amgen over proposed biosimilars of Amgen’s bone drugs Prolia and Xgeva. -
News CPHI Podcast Series: Why we need to consider women in clinical trials
The latest episode of the CPHI Podcast Series with Lucy Chard covers women's health, specifically women's representation in clinical trials, the associated bias, and the impacts on health for this population. -
News US FDA does not approve MDMA therapy for PTSD, requests more data
The MDMA-based therapeutic developed by Lykos Therapeutics, a California-based Public Benefit Corporation (PBC), has been reviewed and unapproved by the US FDA. The regulator has requested additional phase III trial data for further safety and efficacy... -
News Novartis and Viatris latest facing lawsuit over HeLa cell misuse
Global pharmaceutical companies Novartis and Viatris are the latest hit with a lawsuit claim pertaining to alleged misuse of the ‘HeLa’ cell line from the estate of woman whose cancerous tissue cells were taken without consent. -
News Sanofi invests billions into Frankfurt insulin production site
French pharmaceutical company Sanofi have announced an investment of EUR1.3 billion at their existing BioCampus site in Frankfurt am Main for the expansion of insulin production. -
News Novel oral Type 1 diabetes drug gains US FDA IND designation
A University of Alabama at Birmingham startup has gained FDA clearance for Investigational New Drug clinical trials for an oral Type 1 diabetes drug, a milestone for diabetes treatment. -
News A Day in the Life of a Vice President in R&D & Engineering
In the Day in the Life of Series, we've already had the chance to get to know a range of people in various roles in the pharma industry. In the latest interview we get a glimpse into the R&D side of things from Jennifer Sorrells, Vice Presiden...
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance