Pregabalin

Pregabalin
Product Description

Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calciumchannels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.

CTX LifeSciences Pvt. Ltd.

  • IN
  • 2015
    On CPHI since
  • 4
    Certificates
  • 500 - 999
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Generic APIs producer
Intermediates Manufacturer
Specifications
  • CAS Registry Number
    148553-50-8
  • Supplied from
    India

CTX LifeSciences Pvt. Ltd.

  • IN
  • 2015
    On CPHI since
  • 4
    Certificates
  • 500 - 999
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Generic APIs producer
Intermediates Manufacturer

More Products from CTX LifeSciences Pvt. Ltd. (29)

  • Lamotrigine

    Product Lamotrigine

    Lamotrigine is a synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also i...
  • 2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile [Lamotrigine-Schiff Base]

    Product 2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile [Lamotrigine-Schiff Base]

    CTX offers a wide range of intermediates which includes lamotrigine-schiff base. API- lamotrigine. Contact us for more information.
  • Metoprolol Tartrate

    Product Metoprolol Tartrate

    Metoprolol Tartrate is the tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, t...
  • Olmesartan Medoxomil

    Product Olmesartan Medoxomil

    Olmesartan Medoxomil is a synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth...
  • Ondansetron Hydrochloride

    Product Ondansetron Hydrochloride

    Ondansetron Hydrochloride is the hydrochloride salt of the racemic form of ondansetron, a carbazolederivative and a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist with antiemetic activity. Although its mechanism of action has not been fully ...
  • Oxymetazoline Hydrochloride

    Product Oxymetazoline Hydrochloride

    Oxymetazoline Hydrochloride is the hydrochloride salt form of oxymetazoline, an imidazole derivative with a direct acting sympathomimetic property. Oxymetazoline binds to and activates alpha-2 adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constr...
  • Terazosin Hydrochloride Dihydrate

    Product Terazosin Hydrochloride Dihydrate

    Terazosin Hydrochloride is the hydrochloride salt form of terazosin, a quinazoline derivative with adrenergic antagonistic property. Terazosin hydrochloride selectively inhibits alpha-1 adrenergic receptors, resulting in vasodilation leading to decreased peripheral vascular resistance and a ...
  • Xylometazoline Hydrochloride

    Product Xylometazoline Hydrochloride

    A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemi...
  • Alogliptin Benzoate

    Product Alogliptin Benzoate

    Alogliptin Benzoate is the benzoate salt form of alogliptin, a selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition to its effect on glucose levels, alogliptin may inhibit inflammatory respon...
  • Apixaban

    Product Apixaban

    Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots.
  • Chlorthalidone

    Product Chlorthalidone

    Chlorthalidone is a long acting thiazide-like diuretic of the sulfamoylbenzamide class that is devoid of the benzothiadiazine structure. Chlorthalidone directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubu...
  • Brexpiprazole

    Product Brexpiprazole

    Brexpiprazole API is a medication used for the treatment of major depressive disorder, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. It is an atypical antipsychotic.

CTX LifeSciences Pvt. Ltd. resources (1)

  • Video CTX Lifesciences - Your Preferred API, Intermediates Manufacturing & CDMO Partner from India.

    CTX Lifesciences, a vertically integrated Active Pharmaceutical Ingredient (API ) and intermediates manufacturing company supplying & exporting its products across 87 countries. It was established in the year of 2004 in Surat, India and is a part of family owned $600 Million group. This Facility is having over 1000 KL reaction volume and is spread across 38 acres land with sufficient area for expansion. The Active Pharmaceutical Ingredient (API ) products manufactured are backward integrated into intermediates and Key Starting Materials( KSM ), allowing better controls on quality of the products and supply reliability for our customers. This facility is compliant and approved by USFDA, EUGMP, Health Canada, ANVISA, RUGMP, KFDA, COFEPRIS & Iran MOH. The facility is having excellent EHS Management capabilities and certified with ISO 14001:2015 , ISO 45001:2018. This facility is also Ecovadis Rated and Pharmaceutical Supply Chain Initiative ( PSCI ) Audited. Driven...