Positive Data Achieved in Phase 1 Clinical Trial of Reformulated Z160
Based on the data from this study, Zalicus plans to advance Z160 into Phase 2 clinical development for the treatment of neuropathic pain in the second half of 2012.
US-based drug developer Zalicus Inc. has announced the successful completion of a Phase 1 clinical trial evaluating the pharmacokinetics and safety of a new formulation of Z160, a novel oral N-type calcium channel blocker.
In the study, Z160 demonstrated substantial bioavailability and solubility improvements using a novel, proprietary formulation technology.
Based on the data from this study, Zalicus plans to advance Z160 into Phase 2 clinical development for the treatment of neuropathic pain in the second half of 2012.
A previous formulation of Z160 was studied in clinical trials of over 200 subjects and was well tolerated.
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