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4 May 2011

PolyMedix PMX-30063 Effective Against NDM-1 Drug-Resistant Bacteria

The drug candidate is currently undergoing Phase II trial in patients with acute bacterial skin and skin structure infections that are caused by Staphylococcus bacteria.

PolyMedix has said that its lead defensin-mimetic antibiotic, PMX-30063, has shown activity in an in vitro laboratory test against the New Delhi metallo-beta-lactamase-1 (NDM-1) drug resistant strain of Klebsiella pneumonia. NDM-1 is an enzyme carried by bacteria resistant to antibiotics.

 

The drug candidate is currently undergoing Phase II trial in patients with acute bacterial skin and skin structure infections that are caused by Staphylococcus bacteria.

 

The anti-inflammatory properties of PolyMedix's defensin-mimetic compound may benefit in the treatment of several infectious disorders and have distinct characteristics against other antibiotic agents.

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