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15 Aug 2011

Pharmacyclics with NCI to Develop Blood Cancer Drug

Pharmacyclics Inc. will cooperate with the National Cancer Institute to develop PCI-32765, a small molecule inhibitor of Bruton's tyrosine kinase for the treatment of blood cancers.

Biopharmaceutical company Pharmacyclics has signed a five-year cooperative research and development agreement with National Cancer Institute (NCI) to develop PCI-32765, a treatment for hematologic malignancies (blood cancer).

 

PCI-32765 is an orally active small molecule inhibitor of Bruton's tyrosine kinase.

 

Under the agreement, NCI's Division of Cancer Treatment and Diagnosis (DCTD) plans to sponsor Phase 1 and Phase 2 trials of PCI-32765.

 

California-based Pharmacyclics is currently evaluating PCI-32765 in several Phase 2 clinical trials.

 

Pharmacyclics Oncology Developmen

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