Palbociclib (monohydrochloride)

The LCZ696 intermediate is an important organic synthesis and pharmaceutical research intermediate, primarily used for the synthesis of LCZ696 (Entresto). LCZ696 is a dual-acting angiotensin receptor neprilysin inhibitor (ARNI) composed of sacubitril and valsartan, and is widely used in the treatment of ca...

Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.

Monomethyl auristatin E, abbreviated as MMAE, is a synthetic antitumor agent. Due to its toxicity, it cannot be used as a drug alone but is instead conjugated to monoclonal antibodies (mAb). It is an effective antimitotic agent derived from dolastatin, a peptide found in the marine mollusk Dolabella auricu...

Payload Classifications:Auristatin derivativesWe can provide high-quality MMAE and its derived impurities.

VcMMAE (mc-vc-PAB-MMAE) is a biochemical reagent and a component of antibody-drug conjugates (ADCs) as a drug-linker conjugate. It exhibits anticancer activity and is composed of MMAE (a tubulin inhibitor) connected via a Vc linker, as described on Chemicalbook.

AP>99%

特格拉赞  AP≥99.O%

AP>99%

4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester is a pharmaceutical intermediate, primarily used for the synthesis of the active pharmaceutical ingredient Palbociclib.

Trabectedin （Yondelis） 是一种烷化剂，用于治疗既往接受过含蒽环类药物方案的不可切除或转移性脂肪肉瘤或平滑肌肉瘤患者。

VcMMAE (mc-vc-PAB-MMAE) is a biochemical reagent and a part of antibody-drug conjugates (ADCs) as a drug-linker conjugate. It exhibits anticancer activity and is composed of MMAE (a tubulin inhibitor) connected via a Vc linker.

AP>99%  阿维巴坦中间体

ChemExpress have been shortlisted for Best CRO (Contract Research Organization) at the 11th World ADC Awards. 

Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

ChemExpress have received EIR with the conclusion of the inspection, no FDA 483, Observations, was issued by US FDA on August 8th.

ChemExpress CDMO Services brochure (CDMO）

ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. 

ChemExpress ADC Products handbook (ADC)

ChemExpress FTE & FFS Services Flyer (FTE&FFS)

DMF Filed ADC Small Molecule Products