New Developments
Sitagliptin ; Dapagliflozin ; Empagliflozin Intermediates
1) Meldrum's Acid CAS#2033-24-1
2) 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
Monohydrochloride CAS#762240-92-6
3) 1,3-Butanedione,
1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl) CAS#764667-65-4
4) 1-Butanone,
3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)- CAS#823817-56-7
5) N-Boc-Sitagliptin //
N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]carbamic
Acid 1,1-Dimethylethyl Ester; CAS#486460-23-5
6) Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate CAS#769195-26-8
7) Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate CAS#1253055-92-3
Dapagliflozin
Intermediates
1) Phenetole
103-73-1
2) 5 Chloro 2- bromo benzoic acid CAS# 21739-92-4
3) 5-Bromo-2-chlorophenyl)(4-ethoxyphenyl) methanone CAS# 461432-22-4
4) 4-bromo-1-chloro-2-(4-ethoxybenzyl) benzene CAS#461432-23-5
5) 5-Bromo-2-Chloro-4-Ethoxydiphenylmethane
461432-23-5
Empagliflozin Intermediates 1) 5 Chloro 2- bromo benzoic acid CAS#21739-92-4
2) (5-Bromo-2-chlorophenyl)(4-fluorophenyl)methanone CAS#915095-85-1
Sitagliptin ; Dapagliflozin ; Empagliflozin Intermediates
1) Meldrum's Acid CAS#2033-24-1
2) 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine Monohydrochloride CAS#762240-92-6
3) 1,3-Butanedione, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl) CAS#764667-65-4
4) 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)- CAS#823817-56-7
5) N-Boc-Sitagliptin // N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]carbamic Acid 1,1-Dimethylethyl Ester; CAS#486460-23-5
6) Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate CAS#769195-26-8
7) Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate CAS#1253055-92-3
Dapagliflozin Intermediates
1) Phenetole 103-73-1
2) 5 Chloro 2- bromo benzoic acid CAS# 21739-92-4
3) 5-Bromo-2-chlorophenyl)(4-ethoxyphenyl) methanone CAS# 461432-22-4
4) 4-bromo-1-chloro-2-(4-ethoxybenzyl) benzene CAS#461432-23-5
5) 5-Bromo-2-Chloro-4-Ethoxydiphenylmethane 461432-23-5
Empagliflozin Intermediates 1) 5 Chloro 2- bromo benzoic acid CAS#21739-92-4 2) (5-Bromo-2-chlorophenyl)(4-fluorophenyl)methanone CAS#915095-85-1
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