MPLA (Monophosphoryl Lipid A)

MPLA (Monophosphoryl Lipid A)
Product Description

MPLA (Monophosphoryl Lipid A) refers to monophosphoryl lipid A, an effective, safe and non-toxic vaccine adjuvant. It is a highly specific TLR4 agonist that can activate the natural immune response, induce the production of cytokines, and increase the antigen uptake, antigen presentation and activation of specific T cells by antigen-presenting cells such as dendritic cells and monocytes. However, as a bacterial derivative, natural MPLA has many risks such as microbial contamination, unstable quality and sustainable supply. Therefore, our company has developed a fully synthetic monophosphoryl lipid A with a clear product structure and controllable quality, which can ensure the safety and effectiveness of vaccines


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CCCMHPIE

  • CN
  • 2015
    On CPHI since
  • 1 - 24
    Employees
Company types
Association/Government
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Specifications
  • Details
    （1）Adopting full synthesis process, stable structure and high product purity (more than 97%);
    （2）Self-developed process route and product structure, fully confirmed by mass spectrometry, nuclear magnetic resonance, etc.;
    （3）The immunogenicity and safety of various vaccine applications are equivalent to those of bacterial extraction sources;
    （4）Water content, microbial limits, residual solvents and other items all meet the requirements for vaccine use;
    （5）Sufficient safety research and stability inspection of intermediate products and finished products have been carried out;
    （6）Perfect GMP production conditions, large product batches and stable supply.

  • Measured In
    gram
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CCCMHPIE

  • CN
  • 2015
    On CPHI since
  • 1 - 24
    Employees
Company types
Association/Government
View company profile

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