Merck Announces Results of the Phase III Clinical Trial EXPAND
The trial did not meet its primary endpoint of extending the length of time that patients live without their disease getting worse.
Merck has announced the outcome of the Phase III clinical trial EXPAND, which assessed Erbitux? (cetuximab) in combination with cisplatin and capecitabine as a first-line treatment for patients with advanced gastric adenocarcinoma including adenocarcinoma of the gastro-esophageal junction (GEJ).
The trial did not meet its primary endpoint of extending the length of time that patients live without their disease getting worse (progression-free survival – PFS), as determined by independent review.
"We are disappointed that the EXPAND trial did not show a benefit for patients with advanced gastric cancer when Erbitux was added to standard chemotherapy. Patients with advanced gastric cancer currently have few treatment choices and a poor prognosis, and we will contin
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