Life cycle management of branded products

Having decades of hands-on experience on a wide range of (complex) technologies and a many different types of products, our Pharmaceutical experts are able to fully execute and/or support the development of any finished dosage form, formula or process, as well as the transfer and scale-up of a deve...

For us dissolution testing is never a routine test but an essential tool in pharmaceutical formulation development to:

• evaluate the physicochemical properties of drug candidates to select the most appropriate solid form for further development (pre-formulation)
• compare pro...

Our analytical experts know what it takes to bring a pharmaceutical product to the market, from discovery, feasibility to GMP. Having worked with more than 100 unique molecules and even more formulations, we may state that we have faced the most difficult CMC challenges that are involved.
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Excipient testing, composition and variabilityExcipients are either natural / naturally derived or synthetic / semi-synthetic. In all cases the exipients are obtained through chemical processing of a raw material source that usually has an animal, vegetable or mineral origin.

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Our experience in excipient characterization and deformulation of pharmaceutical formulations gives us the opportunity not only to identify and quantify individual excipients in a complex pharmaceutical formulation, but often also confirm the excipient grade, excipient quality and sometimes even the excipi...

Excipients play a central role in the drug development process, in the formulation of stable dosage forms and in their administration. Though excipients were at one time assumed to be “inactive” ingredients, it is now understood that excipients can have an important impact on the pharmaceutical...

Avivia is known amongst the drug development community for being able to deliver successful solutions for complex and challenging formulation and CMC development projects. Typically, pharmaceutical companies and smaller drug development firms approach us with development programs that have derailed...

Avivia offers full product development services to generic drug companies and specialty pharma focused on the development of new improved versions (value-added generics or generic plus) of established drug products.
Although in general the overall aim of value-added generic development projects is focu...

We like to get involved right from the start of a development project and work closely together with our clients and partners on transforming the idea into a product with a solid and commercially viable target product profile (TPP). We set the bar high but always work step by step with a clear focus on...

Excipients can have an important impact on the manufacturability and pharmaceutical performance of a formulation. It’s therefore important to identify and control functionality related characteristics (FRCs) of excipient materials in order to achieve safe, robust and stable products. Expe...

Brochure Avivia independent pharmaceutical development services.
Established in 2005, Avivia is a specialized pharmaceutical development company engaged in CRO service activities, drug repositioning, repurposing and reformulation. Over the past fifteen years, the company has built a solid reputation recognized for its R&D flexibility and ‘out-of-the-box’ approach towards complex and challenging analytical and pharmaceutical development projects. Today, we are the preferred partner for many big pharma, specialty pharma, generic drug companies, academic centra, and smaller drug development firms.