LCZ696

Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.

Eldecalcitol is an active vitamin D3 derivative.

丙酰油菜素内酯，也称为丙酰芸苔素类固醇，是一种植物生长调节剂。它对多种作物非常有效，包括块茎作物（如马铃薯和芋头）、谷物、玉米、棉花、水果蔬菜、豆类、叶菜、果树、木本植物、开花植物和经济作物。

Eribulin mesylate is an antitumor drug used to treat patients with metastatic breast cancer.

Iriteacan mesylate 是一种 DNA 拓扑异构酶 I 抑制剂，IC50 值为 2.2 μM （0.975 μg/mL），可用于癌症研究。

Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

The LCZ696 intermediate is an important organic synthesis and pharmaceutical research intermediate, primarily used for the synthesis of LCZ696 (Entresto). LCZ696 is a dual-acting angiotensin receptor neprilysin inhibitor (ARNI) composed of sacubitril and valsartan, and is widely used in the treatment of ca...

Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.

Monomethyl auristatin E, abbreviated as MMAE, is a synthetic antitumor agent. Due to its toxicity, it cannot be used as a drug alone but is instead conjugated to monoclonal antibodies (mAb). It is an effective antimitotic agent derived from dolastatin, a peptide found in the marine mollusk Dolabella auricu...

Payload Classifications:Auristatin derivativesWe can provide high-quality MMAE and its derived impurities.

VcMMAE (mc-vc-PAB-MMAE) is a biochemical reagent and a component of antibody-drug conjugates (ADCs) as a drug-linker conjugate. It exhibits anticancer activity and is composed of MMAE (a tubulin inhibitor) connected via a Vc linker, as described on Chemicalbook.

AP>99%

ChemExpress have been shortlisted for Best CRO (Contract Research Organization) at the 11th World ADC Awards. 

Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

ChemExpress have received EIR with the conclusion of the inspection, no FDA 483, Observations, was issued by US FDA on August 8th.

ChemExpress CDMO Services brochure (CDMO）

ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. 

ChemExpress ADC Products handbook (ADC)

ChemExpress FTE & FFS Services Flyer (FTE&FFS)

DMF Filed ADC Small Molecule Products