Ground-breaking preclinical data to be presented at AAIC 2017
KalGene’s Alzheimer’s therapeutics candidate, licensed from the NRC (KAL-ABP-BBB), crosses the blood-brain barrier, and reduces amyloid-beta burden in a transgenic rat model after a 4-week treatment.
KalGene Pharmaceuticals, in collaboration with the National Research Council of Canada (NRC), CIMTEC and the McGill Centre for Studies in Aging, have demonstrated that KalGene’s Alzheimer’s therapeutics candidate, licensed from the NRC (KAL-ABP-BBB), crosses the blood-brain barrier, and reduces amyloid-beta burden in a transgenic rat model after a 4-week treatment. The results will be presented by McGill’s Dr.Pedro Rosa-Neto and the NRC’s Dr Balu Chakravarthy at the Alzheimer’s Association International Conference (AAIC) in London, 17 July 2017.
“This is an exciting time for KalGene and we are pleased to share such comprehensive pre-clinical data relating to our therapeutics candidate," says Dr T. Nathan Yoganathan, KalGene’s Chief Executive Officer. "We are committed to advancing the research and development of treatments against Alzheimer's disease, for which disease-modifying therapies are desperately needed."
Based on this preclinical data, KalGene Pharmaceuticals is preparing to conduct Phase I clinical studies.
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