Brand name：Ginkgolide injectionActive ingredients: Bilobalide, Ginkgolide A, Ginkgolide B and Ginkgolide C
Excipients: Glycerol, ethanol.Description:A colorless or pale-yellow clear liquid.
Indication:Ginkgolide injection is indicated for the treatment of mild to moderate cerebral infarction.
Strength:2ml/ampoule (containing 10mg of Ginkgolide)
Dosage and administration
Intravenous infusion. 5 ampoules, total 10ml are used per time. Prior to use, add into a 250ml of 0.9% sodium chloride injection or 250ml of 5% glucose injection for dilution. The prepared solution should be administrated slowly, once a day and with strictly controlled rate of not more than 40 to 60 drops per minute. The whole duration of treatment lasts 14 days.
Pharmacology and toxicology
Non-clinical pharmacodynamics test results show that this product can reduce the stroke score, mortality and cerebral infarct range in a rat model of focal cerebral ischemia induced by a suppository method. It can promote the recovery of electroencephalogram potential amplitude and decrease brain water content in gerbils with cerebral ischemia-reperfusion. It can reduce the brain wet weight, brain index and brain water content in the rat model of four-vessel occlusion cerebral ischemia and reperfusion, and reduce the damage of neurons in hippocampal CA1 area (increasing the density of neurons in this area).
Storage:Sealed and stored in a cool place free from sunlight.PackagingUnopened glass ampoules, 5 ampoules/box
Shelf life:24 months
Specification:YBZ00702011
Approval number:GUOYAOZHUNZI Z20110035
CN
