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9 Jun 2011

Ganetespib Receives Positive Phase II Trial Results

Synta Pharmaceuticals has announced successful clinical responses from the Phase II trial of ganetespib in patients with advanced non-small cell lung cancer.

Synta Pharmaceuticals, a Massachusetts biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs, has reported positive clinical responses from the Phase II trial of ganetespib in patients with advanced non-small cell lung cancer.

 

Ganetespib is an inhibitor of heat shock protein 90, a key facilitator of cancer cell growth and survival. The trial evaluated 76 patients grouped into three cohorts — EGFR mutation, KRAS mutation and neither mutation.

 

Results indicated that the drug showed tumou

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