News
24 Oct 2011
Dynavax & GSK Expand Strategic Alliance for TLR8 Inhibitor
The addition of a new target, TLR8, entitles Dynavax to receive a $3 million milestone payment from GSK.
Dynavax Technologies Corporation and GlaxoSmithKline have announced the expansion of their worldwide strategic alliance focused on toll-like receptor (TLR) inhibitors.
The addition of a new target, TLR8, entitles Dynavax to receive a $3 million milestone payment from GSK.
Subject to reaching sales and development milestones, Dynavax has the potential to receive approximately $200 million in milestone payments over the term of the alliance. Based on preclinical data, Dynavax and GSK will work to develop a TLR8 inhibitor for the treatment of multiple autoimmune and inflammatory diseases.
The activation of TLR8 in myeloid cells yields the
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